OBJECTIVES This study sought to quantify the effect of body mass index (BMI) on early clinical outcomes following coronary artery bypass grafting (CABG). BACKGROUND Obesity is considered a risk factor for postoperative morbidity and mortality after cardiac surgery, although existing evidence is contradictory. METHODS A concurrent cohort study of consecutive patients undergoing CABG from Apr...

BACKGROUND Retinol-binding protein 4 (RBP4) is an adipokine identified as a marker of insulin resistance in mice and humans. Protein tyrosine phosphatase 1B (PTP1B) expression levels as well as other genes involved in the endoplasmic reticulum (ER) stress response are increased in adipose tissue of obese, high-fat-diet-fed mice. In this study we investigated if serum and/or adipose tissue RBP4 ...

abstract background: hope is the most important factor in diabetic patients’ life. the level of hope may be changing among these individuals as a result of chronic nature of diabetes and its complications. when the level of hope increases among these patients, they can resist against physical and psychological complications of diabetes more, accept the treatment better, enjoy life more, and ada...

Objectives: Diabetes itself is known as an independent risk factor for microand macro-angiopathy. However, only a few studies have examined the onset of cardiovascular complications in Japanese patients with type 1 diabetes mellitus (T1DM). In this study, we investigated atherosclerotic changes in Japanese patients with T1DM in terms of age or duration. Methods: The subjects were 41 patients wi...

background: insulin resistance has an important role in pathophysiology of polycystic ovarian syndrome (pcos). yet there are certain controversies regarding the presence of insulin resistance in non-obese patients. objective: the aim was to compare the insulin resistance and various endocrine and metabolic abnormalities in obese and non-obese pcos women.materials and methods: in this cross-sect...

OBJECTIVE To investigate the role of Acylation Stimulating Protein (ASP) receptor C5L2 in skeletal muscle fatty acid accumulation and metabolism as well as insulin sensitivity in both mice and human models of diet-induced insulin resistance. DESIGN AND METHODS Male wildtype (WT) and C5L2 knockout (KO) mice were fed a low (LFD) or a high (HFD) fat diet for 10 weeks. Intramyocellular lipid (IMC...

Prevention and management of obesity largely depends on patient motivation and education and these, in turn, can be greatly facilitated by adequate baseline data on the knowledge, attitude and practice (KAP) of patients. The aim of this study is to assess KAP on obesity among Bangladeshi type 2 diabetics. Under a cross-sectional design 160 type 2 diabetics were selected from outpatient departme...