abstract  introduction: hyperalgesia is considered as one the marked signs of subchronic diabetes mellitus that could affect the life style of the patients. with c onsidering the potential anti-diabetic effect of the medicinal plant withania somnifera (ws)( ashwagandha), this study was designed to investigate the analgesic effect of ws on formalin-induced nociceptive responses (standard formali...

background and objective: although diabetes mellitus is known to be one of the risk factors for dementia but neuropathic changes in the brain of diabetic patients have not been completely revealed. therefore, this research study was done to evaluate structural changes in pyramidal neurons of hippocampal ca1 area of male diabetic rats using golgi-impregnation method. materials and methods: male ...

background and objective: hyperalgesia is one of the marked clinical signs of patients with diabetes mellitus that affects their lifestyle. this study was conducted to assess the anti-nociceptive effect of chronic administration of curcumin in streptozotocin (stz)-diabetic rats using formalin, hot tail immersion, and paw pressure tests. materials and methods: this study was conducted on 40 male...

abstract   introduction: diabetes mellitus accompanies with disturbances in learning, memory, and cognitive skills in the human society and experimental animals. considering the beneficial antidiabetic potential of nigella sativum (ns ), this research study was conducted to evaluate the effect of chronic consumption of ns on learning and memory in diabetic rats using passive avoidance and y-maz...

conclusions troxerutin may reduce the vascular complications and tissue injuries induced by chronic diabetes in rat aorta through increasing the activity of tissue antioxidant system and reducing the level of lipid peroxidation. materials and methods male wistar rats were randomly divided into four groups (n = 8/each): control, control plus troxerutin, diabetic and diabetic plus troxerutin. dia...

objective(s) this investigation was conducted to evaluate the effects of diabetes on the structure and function of testicular tissue. materials and methods diabetes was induced in male adult rats by a single intraperitoneal injection of streptozotocin. body and testicular weight, hormonal analyses, histological and ultrastructural analyses were measured. results the body and testicular weights ...

Background: The potential role of exercise in physiological cardiac hypertrophy is rooted both hormonal and genetic components. Objectives: aim this study was to determine the impact resistance on expression PI3K AKT1 tissue type 2 diabetes (T2D) rats their hypertrophy. Methods: First, 21 male Wistar (220±20 g) were obese with 6-week high-fat diet (HFD) randomly assigned into non-diabetes, cont...

  Abstract  Introduction: Diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli that may resemble and model aspects of painful diabetic neuropathy in humans. This study was designed to investigate the effect of Nigella sativum (NS) on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (STZ)-induced diabetic rats.  Methods: For this...

  Abstract  Introduction: Diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli that may resemble and model aspects of painful diabetic neuropathy in humans. This study was designed to investigate the effect of Trigonella foenum-graecum (TFG) on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (STZ)-induced diabetic rats.  Method...

background: the aim of this study was to evaluate the possible protective effect of sodium selenite on serum, liver, and kidney antioxidant enzymes activities in alloxan-induced type 1 diabetic rats. methods: forty sprague-dawley male rats were randomly divided into four groups; group one as control, group two as sham-treated with sodium selenite by 1 mg/kg intraperitoneal (i.p.) injections dai...