introduction: diabetes mellitus impairs the metabolism of carbohydrates, lipids and proteins, which leads to the dysfunction of the central and peripheral nervous system. this study evaluates the effects of an aloe vera hydro-alcoholic extract on diabetic neuropathy. materials and methods: for this study, 48 healthy male sprague dawley rats(weighed 250-200 g) were randomly divided in to three g...

Emerging evidence suggests that dyslipidemia is an independent risk factor for diabetic neuropathy (DN) (reviewed by Vincent et al. 2009). To experimentally determine how dyslipidemia alters DN, we quantified neuropathic symptoms in diabetic mice fed a high-fat diet. Streptozotocin-induced diabetic C57BL/6 mice fed a high-fat diet developed dyslipidemia and a painful neuropathy (mechanical allo...

Background: Neuropathy is one of the important complications of diabetes. Deficiency of the nerve conduction velocity (NCV) that occurs in both human diabetic neuropathy and animal diabetes models is one of the indicators for diabetic neuropathy. In the present study, we examined the effect of enalapril, angiotensinconverting enzyme inhibitor on NCV, number of endoneurial capillaries and th...

Diabetic neuropathy is a common complication of diabetes. Patients need to be informed of the effects of poorly managed diabetes and appropriate care to prevent diabetic neuropathy. This article provides a brief overview of the main complications associated with diabetes and discusses the different types of diabetic neuropathy. Risk factors in the development of diabetic foot ulcers are identif...

1. Diabetic neuropathy is one of the most common complications of diabetes and oxidative stress has been implicated to play a major role in its pathophysiology. 2. In the present study, we targeted oxidative stress using trolox, an anti-oxidant, in streptozotocin-induced diabetic neuropathy in rats. 3. Compared with control rats, diabetic rats showed significant deficits in motor nerve conducti...

American Diabetes Association American Academy of Neurology O n 8-10 February 1988, a conference on peripheral neuropathy in diabetes was held in San Antonio, Texas, to review the progress achieved in this field over the past few years. A strong impetus for convening this conference was the recent burst of clinical investigations and trials in diabetic neuropathy and a perception that recent re...

BACKGROUND: The aim of this study was to determine the prevalence and risk factors of the sensory neuropathy in type 2 diabetic patients referring to Yazd Diabetes Research Center. Neuropathy is one of the most common complications of both type 1 and type 2 diabetes melli-tus. MATERIAL AND METHODS: This is a cross-sectional study on 2350 diabetic patients (1071 male, 1279 female) referred to Y...

AIMS/INTRODUCTION To measure the elasticity of the tibial nerve using sonoelastography, and to associate it with diabetic neuropathy severity, the cross-sectional area of the tibial nerve and neurophysiological findings in type 2 diabetic patients. MATERIALS AND METHODS The elasticity of the tibial nerve was measured as the tibial nerve:acoustic coupler strain ratio using high-resolution ultr...