background: diabetic ketoacidosis (dka) is the final consequence and life-threatening complication of severe insulin deficiency in type 1 diabetes with occurrence of 20-40%. the aim of this study was to investigate the incidence and predisposing factors of dka and its consequences. methods: this retrospective study was performed on 128 diabetic patients in amirkola children’s hospital in 2005-2...

the number of people with diabetes mellitus is increasing and cataracts are one of the most common causes of visual impairment in these patients. advances in cataract surgery have generally resulted in favorable surgical outcomes. however, surgery may not be safe and effective in individuals who were previously not candidates for surgery or who had limited visual prognosis. many questions remai...

Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 diabetes mellitus-smooth muscle cell phenotype driven by persistent up-regulation of miR-145. This ...

PURPOSE Cilostazol (Pletal), a phosphodiesterase-3 inhibitor, was approved in the United States in 1999 to reduce symptoms of intermittent claudication. Cyclic adenosine monophosphate levels increase from inhibition of phosphodiesterase resulting in anti-platelet, anti-inflammatory, and vasodilatory effects. Diabetes mellitus is a chronic disease that causes endothelial and platelet dysfunction...

introduction diabetic foot is a clinical disorder, which is commonly seen in patients with diabetes mellitus. it is also the major cause of below knee amputation in the world. there are many underlying causes such as neuropathic, ischemic, and infectious causes for diabetic foot. local or systemic complications may develop after snake bite. case presentation we reported a very rare case, involv...

Our aim is to summarize and discuss the recent literature linking diabetes mellitus with heart failure, and to address the issue of the optimal treatment for diabetic patients with heart failure. THE STUDIES LINKING DIABETES MELLITUS (DM) WITH HEART FAILURE (HF) : The prevalence of diabetes mellitus in heart failure populations is close to 20% compared with 4 to 6% in control populations. Epide...

Objective: Increased risk of osteoporosis in patients with diabetes is confirmed. However, earlier biomarker as a diagnostic tool for diabetic osteopenia and osteoporosis is absent on clinical diagnosis. Osteoinductive factor (OIF) is known to be an essential component of the bone matrix. We aimed to investigate the relationship between OIF and 2 diabetes mellitus in combination with osteopenia...

BACKGROUND Diabetes mellitus is a metabolic disorder affecting people worldwide, which require constant monitoring of their glucose levels. Commonly employed procedures include collection of blood or urine samples causing discomfort to the patients. Hence the need for an alternative non invasive technique is required to monitor glucose levels. Saliva present in the oral cavity not only maintain...

conclusions these findings suggest that apelin does not play any significant role in regulating the pain threshold in type 1 diabetes mellitus during exercise training. results plasma apelin level was higher (0.3 vs. 0.1, p < 0.0001) and the tail-flick latency was lower (2.2 vs. 3.8, p < 0.0001) in the d group than in the nd group. after the training program, plasma apelin levels decreased in t...

background: dietary habits are established in childhood and will persist until adulthood, being one of the human health pillars. many diseases of humans have roots in the individuals’ diet, of which dental caries are one of the common infectious diseases. diabetes mellitus is also considered as the most common metabolic disorder in children. objectives: the purpose of this study was to compare ...