Abstract Background Chronic subdural hematoma (CSDH) is a commonly encountered neurosurgical entity, particularly among the elderly population. Surgical intervention by trepanation or burr hole craniostomy remains gold standard approach for symptomatic cases. However, despite excellent outcome, surgical pathway also associated with possible complications, some of which might be fatal, in additi...

Introduction: Postoperative nausea & vomiting (PONV) are common distressing complications of anaesthesia. Pain ,nausea frequently listed by the patient as their most important postoperative concerns. PONV results in increased patientÂ’s discomfort and dissatisfaction. Despite continuing advances anaesthetic surgical technique, both incidence severity remain relatively unchanged. Material Me...

BACKGROUND Postoperative nausea and vomiting is one of the most common complications affecting patients after surgery and causes significant morbidity and increased length of hospital stay. It is accepted that patients undergoing surgery on the bowel are at a higher risk. In the current era of minimally invasive colorectal surgery combined with enhanced recovery, reducing the incidence and seve...

Cushing's syndrome (CS) is common after oral steroid use and has also been reported following topical or inhaled use, but it is extremely uncommon after intranasal administration. This is the case of a 6-year-old child who developed Cushing's syndrome after intranasal application of dexamethasone sodium phosphate for a period of 6 months. Pediatricians and other clinical practitioners should be...

BACKGROUND Postoperative nausea and vomiting (PONV) is one of common complications in patients undergoing laparoscopic cholecystectomy (LC). Aim of this study was to compare the efficacy of subhypnotic (1 mg/kg/h) infusion of propofol with dexamethasone on PONV in patients undergoing LC. METHODS A total of 120 patients were included in this randomized, double-blind, placebo-controlled study. ...

To investigate pituitary-adrenal function in acute uncomplicated falciparum malaria, we performed an overnight dexamethasone suppression test in 13 Vietnamese adults with acute malaria and 6 healthy controls. After blood samples were taken for serum cortisol and plasma ACTH at 23.00 hours on the admission day, 1 mg dexamethasone was given and further samples were taken at 08.00, 16.00 and 23.00...

OBJECTIVE Low-dose dexamethasone facilitates extubation in chronically ventilator-dependent infants with no obvious short-term complications. The objective of this study was to determine the long-term effects of low-dose dexamethasone. METHODS Very preterm (<28 weeks' gestation) or extremely low birth weight (birth weight <1000 g) infants who were ventilator dependent after the first week of ...

Certain organophosphorus esters such as diisopropylfluorophosphate (DFP) cause delayed neuropathy by inhibition of neuropathy target esterase (NTE) keeping neuron in normal function. In this study, effects of neurobion alone and in combination with dexamethasone on DFP–induced delayed neuropathy were evaluated. Thirty-five mice were divided to five groups that each group consists 7 mice. Except...

Hormones regulate hepatic gene expressions to maintain metabolic homeostasis. Ectonucleotide pyrophosphatase/phosphodiesterase 1 has been thought to interfere with insulin signaling. To determine its potential role in the regulation of metabolism, we analyzed its gene (Enpp1) expression in the liver of rats experiencing fasting and refeeding cycles, and in primary rat hepatocytes and human hepa...

Abstract: COVID-19 has dominated the whole world and resulted in increased morbidity mortality. Here we present a case report of 54-years-old man with repeated admissions to hospital after severe pneumonia which on progression lead sepsis bronchitis. There was Dexamethasone induced hyperglycaemia administered antibiotics, corticosteroids, anti-asthmatics COPD preparations. He recurrently admitt...