نتایج جستجو برای: deprenyl

تعداد نتایج: 241  

Journal: :Electrophoresis 2002
Mei-Hsien Lee Mao-Te Chuang Wen-Chi Hou

Plasma amine oxidase (plasma AO, EC 1.4.3.6) is a copper-containing AO which converts benzylamine (BZ) to benzaldehyde, generating hydrogen peroxide and ammonia. The peroxidase was used as an ancillary enzyme to couple hydrogen peroxide to 3-amino-9-ethylcarbazole (AEC) to achieve plasma AO activity after electrophoresis on native polyacrylamide gels. It was confirmed that plasma AO is inhibite...

Journal: :PLoS ONE 2008
Jyothi K. Mallajosyula Deepinder Kaur Shankar J. Chinta Subramanian Rajagopalan Anand Rane David G. Nicholls Donato A. Di Monte Heather Macarthur Julie K. Andersen

Age-related increases in monoamine oxidase B (MAO-B) may contribute to neurodegeneration associated with Parkinson's disease (PD). The MAO-B inhibitor deprenyl, a long-standing antiparkinsonian therapy, is currently used clinically in concert with the dopamine precursor L-DOPA. Clinical studies suggesting that deprenyl treatment alone is not protective against PD associated mortality were targe...

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 1992

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