We have read with interest the article entitled “cagE as a biomarker of the pathogenicity of Helicobacter pylori" by Ramis et al.1. In this study, with a sample size of 57, the authors suggested that cagE is an important prognostic indicator for developing lesions during Helicobacter pylori infection. This suggestion was based on the fact that a statistically signifi cant association was found ...

In Situ Atom Probe Tomography Using Isotopic Tracer article number 2200134, Arun Devaraj and co-workers report that in situ atom probe tomography using 18O isotopic tracer is correlated with ex multimodal characterization computational simulations. This approach validates the outward cation diffusion mechanism as dominant during early stages of oxidation Fe–18Cr–14Ni alloy. a rapid to study hig...

To the Editor: Spread of multi-drug-resistant Neisseria gonorrhoeae is a major public health concern. Effective antimicrobial therapy is a key element in gonorrhea control. However , N. gonorrhoeae has developed resistance to multiple classes of anti-microbial drugs, including β-lactams, tetracyclines, and fl uoroquinolones (1–3). Even an extended-spectrum oral cephalosporin-resistant, cefi xim...

and several characteristics of fl ower morphology (Gaddy, 1987). Multiple species complexes have been identifi ed in this genus and this study focuses on the H. heterophylla complex, containing H. heterophylla The species in this complex are sympatric over portions of their ranges. Vegetative characters have limited taxonomic value, leaving ephemeral fl oral morphology as the only diagnosable f...

Anion-yield spectroscopy using x rays is shown to be a selective probe of molecular core-level processes, providing unique experimental verification of shape resonances. For CO, partial anion and cation yields are presented for photon energies near the C K edge. The O- yield exhibits features above threshold related only to doubly excited states, in contrast to cation yields which also exhibit ...

Lucigenin (LC2+) is frequently used as a superoxide probe. To detect superoxide, lucigenin must be reduced to the lucigenin cation radical (LC.+). We show, using the phosphorylated spin trap 5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide (DEPMPO), that lucigenin stimulates NADPH-dependent superoxide production by endothelial nitric oxide synthase (eNOS). The formation of the DEPMPO-superoxid...

Renal transporter-mediated drug-drug interactions (DDIs) are of significant clinical concern, as they can adversely impact drug disposition, efficacy, and toxicity. Emerging evidence suggests that human renal organic cation transporter 2 (hOCT2) and multidrug and toxin extrusion proteins 1 and 2-K (hMATE1/2-K) exhibit substrate-dependent inhibition, but their impact on renal drug secretion and ...

We propose a scheme for localizing an atom in a four-level configuration inside a classical standing wave field, conditioned upon the measurement of frequency of a weak probe field. In the classical standing wave field, the interaction between the atom and the field is position dependent due to the Rabi-frequency of the driving field. Hence, as the absorption frequency of the probe field is mea...