The conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to isopenicillin N is dependant on the catalytic action of isopenicillin N-synthase (IPNS), an important enzyme in the penicillin and cephalosporin biosynthetic pathway. One of the amino acid residues suggested by the Aspergillus nidulans IPNS crystal structure for interaction with the valine isopropyl group of ACV is prol...

Materials and methods: Prospective analysis of 34 eyes of 17 patients over 40 years of age treated with Allegreto wavefront LASIK system. The study was conducted at MEDEA LASIK Centre, Little Flower hospital, Angamaly. Average patient age was 53.3 years. Pre operative refraction ranged from – 5.75 to + 2.25 diopters(D). Non dominant eyes underwent Presbyopic LASIKan aspheric pupil size dependan...

Military training creates unique noise hazards including high impulse noise content. The need for hearing protection needs to be considered alongside the need for effective voice communication. This requires a hearing protector with high impulse protection that minimally impedes low intensity voice communication. These level dependant devices are called non-linear hearing protectors. A range of...

The basis for primary and secondary prevention of stroke (and also TIA) are both a healthy lifestyle with a healthy diet, non smoking, weight reduction and regular exercise, and consistent treatment of arterial hypertension with a target of < 140 /90 mmHg. The choice of the antihypertensive is depending on concomitant diseases, more important than the class of antihypertensive is treatment to t...

Businesses are increasingly becoming software rich with a plethora of systems varying in age, reliability and ease of use. People working in these businesses are increasingly dependant on their software systems: they are unable to work effectively when “the computer is down”. More generally, businesses need to adapt rapidly to new opportunities and regulations. This requires both changing exist...

The edge-based Spatial Frequency Response (e-SFR) is an established measure for camera system quality performance, traditionally measured under laboratory conditions. With the increasing use of Deep Neural Networks (DNNs) in autonomous vision systems, input signal becomes crucial optimal operation. This paper proposes a method to estimate e-SFR from pictorial natural scene derived SFRs (NSSFRs)...

This thesis deals with the question of how to produce non-photorealistic stippling animations of 3Dmodels. Non-photorealistic animation techniques ought to take into account three important issues that arise when applying 2D drawing styles to 3D model rendering: frame-coherence, scalability and view-dependance, and rendition of animated models. To deal with these issues, the author proposes poi...