Understanding the neural basis of behaviour requires studying brain activity in behaving subjects using complementary techniques that measure neural responses at multiple spatial scales, and developing computational tools for understanding the mapping between these measurements. Here we report the first results of widefield imaging of genetically encoded calcium indicator (GCaMP6f) signals from...

It is widely recognized that citation counts for papers from different fields cannot be directly compared because different scientific fields adopt different citation practices. Citation counts are also strongly biased by paper age since older papers had more time to attract citations. Various procedures aim at suppressing these biases and give rise to new normalized indicators, such as the rel...

We present a modular approach for analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and denoise and deconvolve the spiking activity from the slow dynamics of the calcium indicator. Our approach relies on a constrained nonnegative matrix factorization that expresses the sp...

In order to investigate the temporal and spatial variations of 14 physical and chemical surface water parameters in the Nhue and Day sub-river systems of Vietnam, surface water samples were taken from 43 sampling sites during the dry and rainy seasons in 2007. The results were statistically examined by Mann-Whitney U-test and hierarchical cluster analysis. The results show that water quality of...

Most of distilleries in India use biomethanation process to treat the spent wash generated during the alcohol process, to ensure the effective treatment all distillery industries follow 13 fold dilutions due to which tremendous amount of spent wash is generated. 8 -15 l of spent wash was generated during 1 l of alcohol, thus distillery industries consume more water and produce waste water on a ...

BACKGROUND Burnout is a prolonged response to chronic emotional and interpersonal stressors on the job, defined by 3 dimensions: exhaustion, depersonalization, and reduced personal accomplishment. While there is a growing body of research on burnout in physicians, there is a dearth of literature on burnout in pain medicine physicians. OBJECTIVE This study aimed to determine the incidence of b...

This paper describes the use of Pichia pastoris X-33 as a bioremediator to reduce the chemical oxygen demand (COD), total Kjeldahl nitrogen (TKN), and phosphorus (P-PO(4) (3-)), after culture in parboiled rice effluent supplemented with p.a. glycerol or a glycerol by-product of the biodiesel industry. The greatest reduction in the COD (55%), TKN (45%), and P-PO(4) (3-) (52%) of the effluent was...

Global guidelines for new technologies are based on cost and efficacy data from a limited number of trial locations. Country-level decision makers need to consider whether cost-effectiveness analysis used to inform global guidelines are sufficient for their situation or whether to use models that adjust cost-effectiveness results taking into account setting-specific epidemiological and cost het...

The objectives of the study were: (i) to examine the efficiency of nutrient removal during the treatment of dairy farm effluent in a two-pond system, and (ii) to produce an inexpensive but effective nutrient trap which could be recycled as a nutrient source or soil mulch. The concentration of chemical oxygen demand (COD), biological oxygen demand (BOD), nitrogen (N), phosphorus (P) and potassiu...

The characterization of landfill leachate has been well established. However, its biodegradation properties have not been well reported. Therefore, this research was undertaken to investigate the biodegradability of semi-aerobic sanitary landfill and the ratio of the biological oxygen demand (BOD) to chemical oxygen demand (COD) BOD5/COD, COD fraction on leachate from Pulau Burung landfill Site...