Hepatocyte nuclear factor-1α (HNF-1α) is found in the kidneys, spleen, thymus, testis, skin, and throughout the digestive organs. It has been found to promote the transcription of various proteins involved in the management of type II diabetes, including dipeptidyl peptidase-IV (DPP-IV). Phenolic compounds from berries and citrus fruits are known to inhibit DPP-IV, but have not been tested for ...

Zaman N, Afaq F, Khan N, Syed DN, and Mukhtar H. Delphinidin, a major anthocyanin in pigmented fruits and vegetables is a potent inhibitor of epidermal growth factor receptor and its downstream signaling pathway. The 97 Annual Meeting of the American Association for Cancer Research, Washington, DC, USA (April 1-5, 2006). CONCLUSIONS: This study identifies an abundant fruits and vegetables based...

Increasing evidence suggests that anthocyanins, as natural antioxidants, exert anti-carcinogenic, anti-inflammatory, vaso-protective and anti-obesity effects when tested in vitro or in vivo. Blackcurrant (Ribes nigrum L.) berries are a rich source of anthocyanins with concentrations up to 4-fold greater than that of other common fruits. However, there is a paucity of information on how blackcur...

Background We have previously reported the effect of Anthocyanin and cAMP modulators on maturation and apoptosis of sheep oocytes. In this study, we investigated the reduction capacity and apoptotic gene expression results at MII sheep oocytes. MaterialsAndMethods Good ovine Cumulus-oocyte complexes (COCs) were transferred to Pre-IVM medium, then to two type IVM mediums: 1) 0.1μg/ml Delphinidin...