The anterior approach is a well-known surgical technique for the treatment of degenerative diseases of the lumbar spine. Through this approach is possible to perform arthrodesis, arthroplasty, discectomy, corpectomy to treat a lot of degenerative conditions. The ALIF procedure is one of the most widely used technique, and is argued to have biomechanical advantages over posterior approaches for ...

Degenerative changes in the intervertebral discs have been recognized by pathologists for a considerable time. They were described by Wenzel (1842) and were also studied by Rokitanski (1855) and by many other pathologists. Extensive studies by Schmorl (1929), begun in Dresden in 1925 on routine autopsy material, revealed the great frequency of degenerative changes in the intervertebral discs an...

INTRODUCTION: Intervertebral disc (IVD) degeneration is an important clinical problem that often contributes to low back pain and degenerative disc diseases. Degeneration of the IVD induces anulus tears and fissures, which can cause severe discogenic low back pain. Because the IVD has little potential to self-regenerate, treatment of degenerative disc disease is one of the most challenging clin...

INTRODUCTION Total disc replacement(TDR) has been suggested for surgical method to treat degenerative disc disease of the cervical spine because it decompresses nerves and preserves motion segments. The short-term outcomes of the TDR of cervical spine has been well reported to treat degenerative disc diseases as a motion preservation technique in spite of some clinical controversies such as imp...

OBJECTIVE As a main cellular component within the disc, nucleus pulposus (NP) cells play important roles in disc physiology. However, little is known on the biologic hallmarks of human NP cells. Therefore, the present study aimed to address the features of human NP cells. METHODS Human NP samples were collected from normal cadavers, patients with scoliosis and disc degeneration as normal, dis...

Low back pain and degenerative disc disease are a significant cause of pain and disability worldwide. Advances in regenerative medicine and cell-based therapies, particularly the transplantation of mesenchymal stem cells and intervertebral disc chondrocytes, have led to the publication of numerous studies and clinical trials utilising these biological therapies to treat degenerative spinal cond...

STUDY DESIGN Lumber disc arthroplasty is a technological advancement that has occurred in the last decade to treat lumbar degenerative disk diseases. PURPOSE The aim of this retrospective study was to establish the impact and outcomes of managing patients with lumbar degenerative disk disease who have been treated with lumbar total disc arthroplasty (TDA). OVERVIEW OF LITERATURE Several stu...

Background: Degenerative spinal disease increases in proportion to life expectancy. Surgical treatments that play an essential role the management of degenerative have evolved from open surgery minimally invasive as well endoscopic surgery. Advanced pathological understanding, diagnostic imaging, and instrument progress support for The study aims report current situation treat diseases Departme...