BY THE BEGINNING of the twentieth century, many diseases could be causally explained by the germ theory. However, other important diseases defied every attempted explanation. One such disease was beriberi which, in some groups, was responsible for more deaths than were all the infectious illnesses combined.' To explain how beriberi was caused, a new theory of disease was developed, the deficien...

In recent years, we have witnessed several important paradigm shifts in understanding the molecular basis of liver disease in alpha-1-antitrypsin (AT) deficiency. These shifts have become possible as a result of a number of advances in research on the cell biology of aggregation-prone mutant proteins and in research on the pathobiological mechanisms of liver disease in general. Late-breaking re...

background: there is a growing concern about the high prevalence of vitamin d deficiency and its relationship with variety of diseases worldwide. the objective of this study was to determine the prevalence of vitamin d deficiency and its relationship with pregnancy adverse effects in yazd. methods: this was a cross sectional study conducted among 200 nulliparous women from october 2013 to april...

this study was aimed to determine prevalence of vitamin d deficiency and rickets in children with cholestatic liver diseases. forty eight children with established cholestatic liver disease who referred to gastrointestinal clinic of children medical center (tehran, iran) between april 2010 and march 2011 were enrolled in a cross-sectional study. laboratory analysis including calcium, phosphate,...

Vitamin D is a lipid-soluble substance that has two forms, vitamin D2 (ergocalciferol) and D3 (cholecalciferol). UV light the main source of induces conversion 7-dehydrcholestrol to in skin. Food sources contain high amount are egg yolk, fish, liver. Several studies revealed wide prevalence deficiency Vit. among healthy population, addition, different diseases have relation with their inadequac...

Traditional Chinese medicine formulates treatment according to body constitution (BC) differentiation. Different constitutions have specific metabolic characteristics and different susceptibility to certain diseases. This study aimed to assess the characteristic genes of gan-shen Yin deficiency constitution in different diseases. Fifty primary liver cancer (PLC) patients, 94 hypertension (HBP) ...