Background. A paradoxical increase in cardiovascular events has been reported with intensively lowering diastolic blood pressure (DBP). This J-curve phenomenon has challenged the aggressive lowering of blood pressure, especially in patients with coronary artery disease. Objective. Our objective was to study the effects of low DBP on mortality and determine a threshold for which DBP should not b...

Laboratory experiments were carried out to investigate wastewater organics as the precursors of disinfection byproducts (DBPs) in drinking water supply. The focus was on the change in wastewater DBP precursors during biological degradation under simulated natural conditions. The wastewater and its treated secondary effluent were characterized for DBP formation potential (DBPFP) and DBP speciati...

The albumin D site-binding protein (DBP) governs circadian transcription of a number of hepatic detoxification and metabolic enzymes prior to the activity phase and subsequent food intake of mice. However, the behavior of mice is drastically affected by the photoperiod. Therefore, continuous adjustment of the phase of circadian Dbp expression is required in the liver. Here we describe a direct ...

The "all carbon" organic solar cells (OSCs) based on the homocyclic molecule tetraphenyldibenzoperiflanthene (DBP) as a donor and C60 as an acceptor were comprehensively characterized. The optimized planar-mixed heterojunction device with a DBP:C60 mixture ratio of DBP : C60 (1 : 2) exhibited a power conversion efficiency of 4.47%. To understand why DBP possesses such advantageous characteristi...

AIMS Guidelines recommend blood pressure (BP) in hypertensive patients should be <140 systolic BP (SBP) and <90 diastolic BP (DBP) mmHg. This analysis assessed goal rate achievement in hypertensive patients receiving olmesartan-based treatment in the OLMEBEST study. METHODS Patients with essential hypertension (DBP > or = 90 mmHg and <110 mmHg) received open-label olmesartan medoxomil 20 mg/d...

It has been suggested that transfer functions to estimate central aortic systolic blood pressure (SBP) and BP waveform parameters (i.e., augmentation index) may be less accurate in patients with type 2 diabetes mellitus (T2DM). However, these observations have not confirmed a large sample, which was the aim of this study. Consecutive without T2DM undergoing coronary angiography at Royal Hobart ...

The relative importance of systolic (SBP) versus diastolic blood pressure (DBP) and other combinations of SBP and DBP in the prediction of stroke have been re-examined in a long term cohort study of 10,541 men and women aged 45-64 in West Scotland. During a mean follow-up of 11.6 years 1, 616 deaths occurred, among which 160 (9.9% 80 male, 80 female) were due to stroke. In a multiple logi...

Chlorophyllin (CHL) is a potent antimutagen in vitro, an effective anti-carcinogen in several animal models, and significantly reduced urinary biomarkers of aflatoxin B(1) (AFB(1)) exposure in a human population. Here we report an expanded analysis of CHL chemoprevention using the potent environmental hydrocarbon dibenzo[a,l]pyrene (DBP). A dose-dose matrix design employed over 12 000 rainbow t...

INTRODUCTION: Both Demineralized Bone Powder (DBP) and BMP-2 stimulate endochondral osteogenesis in vivo. Nevertheless, the relationship between BMP-2 and skeletal induction by DBP is unknown. When human dermal fibroblasts (hDFs) are cultured with DBP in a porous collagen sponge for 7 days, cartilage-specific genes, aggrecan and collagen II, are upregulated and cartilage matrix accumulat es aro...