Cystic fibrosis (CF) is the most common severe autosomal recessive disorder caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The frequencies, types and distributions of mutations vary widely between different populations and ethnic groups. The aim of this study was to perform a comprehensive analysis of the C...

up almost 20% of all ovarian neoplasms. Although they are almost always benign tumors, the rare development of cancer deserves emphasis. The most common malignant change in a dermoid cyst is squamous cell carcinoma, followed by adenocarcinoma and carcinoid tumor (1-3). Primary of ovarian carcinoid tumors are uncommon and the majority of them are associated with mature cystic teratomas (4). Robb...

The use of sputum cultures to guide the antimicrobial treatment of patients with cystic fibrosis has been questioned. Bacterial growth and antibiotic susceptibility patterns of 33 culture pairs from sputum and contamination free endobronchial swabs from 14 patients with cystic fibrosis were compared. As expected, Pseudomonas aeruginosa of the mucoid and non-mucoid type, Staphylococcus aureus, a...

In the period 1968-76, necropsies were carried out on 30 patients who had been treated by long-term intermittent maintenance haemodialysis. Fourteen of these patients developed bilateral cystic disease of the kidney. Clinical, pathological, and radiological investigation of these patients when they first presented did not reveal any evidence of renal cystic change. The main complications of thi...

The life expectancy for patients with cystic fibrosis has improved remarkably over the last 20 years. Progressive deterioration of pulmonary function continues despite the aggressive use of antimicrobials. The absence of fever, neutrophilia, and systemic symptoms suggest that during pulmonary exacerbations other non-bacterial factors may have played a part. Some have suggested respiratory virus...

is clinically and radiologically important because it mimics tumor-like lesions in the sellar area and may produce mass effects. Xanthomatous hypophysitis is a type of primary hypophysitis with a very low prevalence. In previously reported cases (1-3), patients with xanthomatous hypophysitis sometimes presented with a headache, sexual dysfunction, and/or diabetes insipidus. A pituitary lesion w...

Solitary fibrous tumors are unusual neoplasms that are rarely found in the liver parenchyma. They are usually described as hard, grayish white, well-defined lesions. Predominant cystic change in a solitary fibrous tumor is an unexpected finding, with only a few previous cases reported in the literature, two of which are localized in the head and neck region. Herein, we report a unique case of s...

Introduction Cystic fibrosis (CF) is a serious, multi-system disease. In the Caucasian population CF most common autosomal recessive disease, which happens for 1 person in 3,500 births [1]. course of CF, there dysfunction many organs, mainly respiratory and digestive systems. Symptomatic treatment cystic very important. The change daily eating habits, use proper breathing techniques psychothera...

cystic hygroma (ch) in the cervical region presents as a challenge to the anesthetist. the anaesthetic difficulties are usually associated with ch because of tumor extension into the mouth, airway management, thoracic extension, hemorrhage, involvement of pretracheal region, post operative respiratory obstruction and coexisting anomalies (down syndromes, turner syndromes and congenital cardiac ...