BACKGROUND The plasma level of cystatin C is a better marker than plasma creatinine for successful aging. It has been assumed that the advantage of cystatin C is not only due to it being a better marker for glomerular filtration rate (GFR) than creatinine, but also because an inflammatory state of a patient induces a raised cystatin C level. However, the observations of an association between c...

BACKGROUND AND PURPOSE Cystatin C, a serum measure of renal function, has been reported as a strong predictor of risk of death and cardiovascular events in elderly people. We investigated the association between cystatin C and first-ever stroke and evaluated the predictive value of cystatin C in cardiovascular events and death from all causes based on the outcomes of a 5-year follow-up. METHO...

BACKGROUND Polycystic ovary syndrome (PCOS) causes an increased risk of metabolic cardiovascular syndrome. Also, cystatin C serum levels are associated with the risk of cardiovascular events in metabolic syndrome patients. OBJECTIVE To investigate the relationship between cystatin C in PCOS patients. MATERIALS AND METHODS 35 women with PCOS were compared to 35 women with healthy matched age...

BACKGROUND Cystatin C is a new interesting marker of glomerular filtration rate (GFR). However, data regarding its biological variance are scarce and conflicting. The ability of cystatin C to longitudinally follow renal function in patients therefore remains questionable. METHODS 12 healthy subjects (6 men and 6 women) were included in the final statistical analysis. Serum creatinine, plasma ...

background: acute kidney injury (aki) is a common and life-threatening complication following coronary artery bypass graft (cabg). neutrophil gelatinase-associated lipocalin (ngal) and cystatin c have shown to be good predictive factors for aki. recently, there has been a growing interest in the use of hypertonic saline in cardiac operations. the purpose of this study was to evaluate the prophy...

OBJECTIVES To explore the correlation between serum cystatin C level and elderly hypertension with coronary heart disease patients. METHODS 500 hypertensive patients combined coronary heart disease were selected by coronary angiography. 321 of them were elderly patients with hypertension (male 204, female 117), and 400 of them were elderly patients with coronary heart disease (male 257, femal...

BACKGROUND Cystatin C is a marker of kidney function that may also be associated with inflammation. In this study, we compared the relative strengths of association of cystatin C and estimated glomerular filtration rate (eGFR) with inflammatory biomarkers. METHODS We measured serum cystatin C and creatinine in 990 outpatients with coronary artery disease enrolled in the Heart and Soul Study. ...

Corresponding author: Ji Hyun Lee http://orcid.org/0000-0002-5671-0875 Department of Internal Medicine, Catholic University of Daegu School of Medicine, 33 Duryugongwon-ro 17-gil, Nam-gu, Daegu 42472, Korea E-mail: [email protected] Cystatin C is entirely filtered by the kidney glomerulus and metabolized by the proximal tubule, and it is mainly used as a biomarker of renal function. It was first ...

PURPOSE Cystatin C has a higher correlation with glomerular filtration rate and a more significant clinical prognosis than creatinine. We sought to determine whether it is a marker of renal function different from creatinine (cystatin C potentially superior to creatinine), in patients with systemic lupus erythematosus. MATERIAL AND METHODS 37 patients with systemic lupus erythematosus were ev...

With the development of highly active antiretroviral therapy, chronic kidney disease has become a prominent cause of morbidity in individuals infected by HIV. Because serum creatinine has significant limitations in this specific population, cystatin C is emerging as a promising biomarker for both the evaluation of glomerular filtration rate (GFR) and the detection of drug-induced kidney injury....