It has long been known that pyrazole and fused pyrazole compounds possess numerous chemical, biological, medicinal and agricultural applications because of their versatile biological activities appearing as antimicrobial, antiviral, antitumor, anti-inflammatory, antihistaminic, pesticidal, antifungal and antipyretic agents. On the other hand, cyclic oxalyl compounds of type 1 have been used suc...

Total alkalinity is one of the important parameter in regulation seawater carbonate chemistry system to determine capacity water neutralize acid. In this paper, a new proton pump membrane was successfully modified using polyvinylpyrrolidone (PVP) as supporting material due its excellent chemical properties. The surface morphology thoroughly studied Scanning Electron Microscope (SEM), which show...

The syringopeptins are a group of antimicrobial cyclic lipodepsipeptides produced by several plant-associated pseudomonads. A novel syringopeptin, SP508, was shown to be produced as two homologs (A and B) by Pseudomonas syringae pv. lachrymans strain 508 from apple and to structurally resemble syringopeptin SP22. SP508 differed from SP22 and other syringopeptins by having three instead of four ...

Two new cyclic hexapeptides, mollamides B (1) and C (2), were isolated from the Indonesian tunicate Didemnum molle along with the known peptide keenamide A (3). The structures were established using 1D and 2D NMR experiments. The relative configuration of mollamide B at the thiazoline moiety was determined using molecular modeling coupled with NMR-derived restraints. Their absolute configuratio...

Gramicidin S (GS) is a cyclic cationic antimicrobial peptide (CAP) with a wide spectrum of antibiotic activities whose usage has been limited to topical applications owing to its cytotoxic side effects. We have synthesized tetrahydrofuran amino acid (Taa)-containing GS analogues, and we have carried out conformational analysis and explored their structure activity relationships by evaluating th...

A sensitive method for the determination of the herbicide pindone by adsorptive stripping voltammetry using a hanging mercury drop electrode at pH 4.0 was described. The cyclic voltammogram of pindone demonstrates that compound was adsorbed at the surface of mercury electrode, and the overall reduction process was under controlled diffusion. The adsorptive peak was observed at −0.3 V, and peak ...

Electrochemical behaviour of isatin monohydrazone (IM) on a hanging mercury drop electrode in the Britton-Robinson (B-R) buffer solution of pH = 2.00 – 9.00 has been investigated using square-wave voltammetry (SWV) and cyclic voltammetry (CV) techniques. In the pH range of 2.00 – 5.00, the voltammogram of IM exhibited a single cathodic irreversible peak. When the pH value exceeds 5.00, a new ca...

OIMOMI found that Escherichia coli 443, E. coli 5 and Enterococcus 1294 produced an ether-extractable compound active against Candida1), and applied this ether extract locally for treatment of nasal complications of the common cold and trychophytiasis of the feet.2,3) The results suggested some effect of this crude extract, which was found also to inhibit growth of staphylococci and streptococc...

Lactobacillus plantarum and Leuconostoc mesenteroides play a prominent role as functional starters and predominant isolates in the production of various types of antimicrobial compound-containing fermented foods, especially including kimchi. In the case of the bioactive cyclic dipeptides, their racemic diastereomers inhibitory to bacteria and fungi have been suggested to come solely from Lactob...