The measurement of pulmonary artery pressure and resistance is crucial in the management of older patients with cyanotic congenital heart disease. This is especially important in patients who have had previous palliative surgery or known right ventricular outlet obstruction.' The ability to measure pulmonary artery pressure is often hampered by the presence of significant derangements of cardia...

Lactobacilli are rod shaped gram positive bacteria that naturally colonize the human gastrointestinal and genitourinary tracts and occasionally cause disease in humans. Lactobacillus infections are found in patients who are immunocompromized or have severe comorbidities. We report Lactobacillus endocarditis in a 17-year-old adolescent girl with cardiac prosthetic material following surgical cor...

BACKGROUND Mitochondrial biogenesis program in heart appears to exhibit adaptive remodeling following biomechanical and oxidative stress. The adaptive mechanisms that protect myocardium metabolism during hypoxia are coordinated in part by nitric oxide (NO). OBJECTIVE To observe mitochondrial biogenesis and nitric oxide synthase (NOS) expression in hearts of congenital heart disease with cyano...

PURPOSE OF REVIEW Patients with congenital heart disease have a number of risk factors for the development of chronic kidney disease (CKD). It is well known that CKD has a large negative impact on health outcomes. It is important therefore to consider that patients with congenital heart disease represent a population in whom long-term primary and secondary prevention strategies to reduce CKD oc...

A female newborn probably with a variant form of galactosialidosis is described. The patient, in addition to the common findings seen in early infantile forms of classical galactosialidosis, displayed an unusual combination of congenital malformations including complex cyanotic congenital heart disease with dextrocardia and situs inversus.

OBJECTIVE To evaluate changes in cognitive and academic functioning following cardiac surgery in children with congenital heart disease. DESIGN A prospective cross sectional study in which patients were assessed immediately before treatment and 12 months later. PATIENTS Three groups of children aged 3.5-17 years: a group with congenital heart disease awaiting surgery, another awaiting bone ...

Venous blood lactic acid and pyruvic acid concentrations and lactate-pyruvate ratio were studied in 42 normal adults, 16 normal children and 18 children with congenital heart disease. There was elevation of resting values in children as compared with adults, but no significant change of values of resting children with congenital heart disease as compared with normal children. Following a standa...

Our present focus on the hypoxic immature heart is driven by clinical urgency: cyanotic congenital cardiac malformations remain the single largest cause of mortality from congenital defects and ischemic heart disease is no more the disease of the fifth and older decades but its origin as well as risk factors are present already during early ontogeny. Moreover, the number of adult patients opera...

Aim: Congenital heart disease is the most common congenital problem in children. Presentation can vary from asymptomatic accidental finding to severe cardiac decompensation and death. Early recognition has great implications on prognosis. To study age, gender distribution and frequency of congenital heart disease in children referred to echocardiography in a single hospital in Zarqa. Methods: T...

Tetralogy of Fallot (TOF) is the most frequent cyanotic congenital heart disease . According to a recent prospective study on the prevalence of congenital heart diseases in Germany, 2 .5% of all neonates suffer from TOF [1] . Without treatment this frequent occurring CHD has a high morbidity and mortality . Surgical treatment has improved this grim outlook dramatically . In the following, the r...