Bullous pemphigoid is a rare complication of immune checkpoint inhibitor treatment. We report case pembrolizumab-induced bullous in patient with malignant melanoma and concomitant cutaneous squamous cell carcinoma that regressed. A 77-year-old woman metastatic 3-year history growing skin nodule on her left calf was treated pembrolizumab. Histopathological examination the established diagnosis c...

PURPOSE Forkhead box p3 (Foxp3) positive T regulatory cells (Tregs) have a functionally immunosuppressive property that prevents effector cells from acting against self in autoimmune diseases or a tumor. It is known that Tregs may be highly relevant in cancer progression. Dendritic cells (DCs) induce cutaneous immune response, however several studies have suggested that DCs are involved in immu...

A woman presenting with vulval lesions is to be examined and evaluated further before giving her the definitive diagnosis proposing treatment. As differential may vary from benign like lichen sclerosus, intraepithelial neoplasia or malignant squamous cell carcinoma. We are a case report wherein 70 year presented features similar carcinoma but was diagnosed as pseudoepitheliomatous hyperplasia o...

malignant tumors of pancreas are usually primary neoplasms and pancreatic metastases are rare findings. we are reporting a case of squamous cell carcinoma (scc) of the esophagus with pancreatic metastasis. a 59-year old woman was admitted with chief complaint of abdominal pain and mass. she was a known case of esophageal scc since 4 years before when she had undergone transthoracic esophagectom...

conclusions prognosis of this type of tumor, apart from its size and differentiation level, depends on infiltration in tumor-surrounding tissue, perineural and perivascular spread. therefore, it is always necessary to analyze the removed skin especially on margins. introduction squamous cell carcinoma is the most common type of lip and oral cavity cancers. in majority of cases it follows quite ...

squamous cell carcinoma (scc) of the buccal mucosa accounts for 23% to 37% of all intraoral cancers, the prognosis is generally poor. we reported a case of local invasion of buccal squamous cell carcinoma. a 32-year-old man referred to the clinic with a chief complaint of swelling in the right cheek region that initiated from 6 months ago and rapidly grow from one month ago. history of the pati...

patients. in this disease the risk of many malignancies is increased, of which the most important is non- hodgkin lymphoma of the small intestine. other malignancies include adenocarcinoma of the small intestine and squamous cell carcinoma of the esophagus. to the best of our knowledge, thus far only one case of celiac disease associated with hypopharyngeal squamous cell carcinoma has been repo...

background: lung cancer ranks among the most common and most lethal malignancies worldwide. once vascular or lymphatic invasions occur, metastatic dissemination to distant sites is common. bone, liver, adrenals, and brain are the most frequent sites of the distant disease. in this study we present a case of squamous cell carcinoma of lung with metastasis of the left knee bursa.case presentation...

PURPOSE Tobacco smoking is a risk factor for several cancers. The risk of cutaneous malignancies related to smoking, however, is relatively unknown. We investigated the possible association between smoking and skin cancer. PATIENTS AND METHODS A hospital-based case-control study was performed that included 161 patients with squamous cell carcinoma, 301 with nodular basal cell carcinoma, 153 w...