The prospective, multicenter, double-blind study presented in this report evaluated whether or not intravenous (IV) administration of doripenem, a carbapenem with bactericidal activity against gram-negative and gram-positive uropathogens, is inferior to IV administration of levofloxacin in the treatment of complicated urinary tract infection (cUTI). Patients (n = 753) with complicated lower UTI...

statement of the problem: refractory nocturnal enuresis possesses a heavy psychosocial burden for the affected child. only a 15% spontaneous annual cure rate is reported. purpose: this patient-level meta-analysis aimed to evaluate the efficacy of rapid palatal expansion to treat nocturnal enuresis among children. materials and method: a sensitive search of electronic databases of pubmed (since ...

BACKGROUND Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS In this study, we searched the PubMed, EmBase, and Cochrane databases for randomized controlled trials published until September 20...

The combination of platinum, vinblastine, and bleomycin was first used at Indiana University in 1974. Thirty of 47 patients (64%) survived for 5 years, and 27 (57%) are currently disease free (NED) and cured of their neoplasm. From 1976 to 1978, 78 consecutive patients were entered on a random prospective study that indicated that equal therapeutic results could be achieved with a lower dosage ...

the effect of a combination of oxantel- pyrantel with a single dose of 10 mg/ kg body weight on trichuris trichiura, ascaris, trichostrongylus spp. and ancylostoma duodenale has been evaluated among the population of two rural areas in khuzestan, southwest iran (41 persons) and isfahan, central (30 persons). all patients were infected with trichuris trichiura and some simultaneously with one or...