fourier transform infrared (ftir) and gel permeation chromatography (gpc) wre respectively utilized in determining the changes in isocyanate (nco) concentration and molecular weight (mw) and its distribution (mwd) in polyurethanes during their cure and postcure stages. samples, originally cured at 45°c, were taken through accelerate aging tests at various temperatures. the ftir and gpc analytic...

since reusing waste tire as a cheap filler is considerably high, in this study, recycled rubber to replace nr/br is used up to 15 phr and the positive and negative aspects of the rubber powder and reclaimed rubber in the physical, dynamical and processing properties are evaluated. the results showed that in the presence of recycled rubber, the cure rate, crack growth resistance, tear strength a...

We propose a model that characterizes and links the complexity and diversity of clinically observed hepatitis C viral kinetics to sustained virologic response (SVR)-the primary clinical end point of hepatitis C treatment, defined as an undetectable viral load at 24 weeks after completion of treatment)-in patients with chronic hepatitis C (CHC) who have received treatment with peginterferon alph...

Survival analyses are greatly used in medical research especially frailty models which are mostly used to account for heterogeneity in time-to-event. Over the years treatment of cancer has progressed with some patients being cured from different type of cancer. Survival analysis is more focused on subjects that are less at risk of recurrences, metastasis or death after the first treatment as th...

In treating and controlling cancer, the most dramatic evidence of progress is that seen in childhood cancer. Once almost uniformly fatal, pediatric cancer has become a commonly curable illness in the last 30 years. For children diagnosed with cancer, the current 5-year cancerfree survival rate is 79%, and the 10-year survival rate is approaching 75% (Rowland et al., 2004). These figures already...

Cure rate estimation is an important issue in clinical trials for diseases such as lymphoma and breast cancer and mixture models are the main statistical methods. In the last decade, mixture models under different distributions, such as exponential, Weibull, log-normal and Gompertz, have been discussed and used. However, these models involve stronger distributional assumptions than is desirable...

The proportional hazards curemodel generalizes Cox’s proportional hazardsmodel which allows that a proportion of study subjects may never experience the event of interest. Here nonparametricmaximum likelihood approach is proposed to estimating the cumulative hazard and the regression parameters. The asymptotic properties of the resulting estimators are established using the modern empirical pro...