The 2 Spanish groups, Grupo Español de MM (GEM) and Programa para el Estudio de la Terapéutica en Hemopatía Maligna (PETHEMA), report on the superiority of both event-free survival (EFS) and overall survival (OS) in patients in whom complete response (CR) status was achieved, compared with lesser response categories (near-CR [nCR], very good partial response [VGPR], partial response [PR]), in a...

PRESENTATION OF THE CASE A 61-year-old man undergoes a sigmoid colectomy for a T3N1 (two of 18 nodes) adenocarcinoma of the sigmoid colon. He recovers well and receives 6 months of adjuvant FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin) uneventfully. At his first follow-up visit, the oncologist recommended every 3 month visits for a physical, liver function tests, and carcinoembryonic ant...

Corporations, consumers, the uninsured and doctors had all been clamoring for reform, and the question of why the project failed has nagged at Cutler ever since, especially as the problems have continued to worsen. In the years since he left Washington, which was in 1994, the ranks of the uninsured have surged, from 35 million people to 45 million. There are also serious gaps in the quality of ...

Combination antiretroviral therapy (cART) is highly effective at preventing morbidity and mortality due to infection with human immunodeficiency virus (HIV), but does not eradicate the virus. Consequently, cART must be administered life-long. Recent progress has stimulated research towards a cure of HIV infection. Approaches under investigation include hematopoietic stem cell transplantation, l...

I. The first and the foremost being the incision in the median raphe ; [ [ . The second is the bringing ̂ together of the cut ends of the everted tunica vaginalis near the upper end of the Epididymis by a catgut stitch ; and III. The third is the washing out of the cavity with ether. (1) Perchloride of mercury lotion (1 in 1,000) ; (2 ) Carbolic lotion ( 1 in 20) ; or ( 3) Pure sulphuric sther 2...

Living in the computer and information age, most people are familiar with the concept of digital information. Computer hard drives and CD’s hold a certain number of bits of information. The stored information can readily be transformed into music, pictures or documents. Information has an objective reality and is deeply connected to fundamental “laws of nature.” Evolution is about the copying a...

osteo-malacia, oven the acute form, developing during pregnancy, may be cured by the injection of adrenalin. This interest in Germany has become so general as to lead to this method of treatment being ordinarily spoken of as the " Bossikur." The interest in the subject has been extended very greatly, during the last few months, by further assertions, of Professor Bossi, based on experimental wo...