One type of congenital intrasphenoidal meningoencephalocele is remnant of lateral craniopharyngeal (Sternberg's) canal. We present a case of a 23-year girl with 10-month history of right side CSF rhinorrhea. CT scan, MRI revealed congenital meningoencephalocele and CSF leak from middle fossa to right side of sphenoid sinus, and there were bony defects at the floor of the anterio...

Abstract Background Cerebrospinal fluid (CSF) rhinorrhea usually presents as unilateral clear thin nasal drainage, is caused by a direct communication from the subarachnoid space to sinonasal cavities and can lead intracranial infection, pneumocephalus, or death. Diagnosing CSF be challenging. While gold standard for leak confirmation surgical exploration, testing beta-2 transferrin (B2Tf) via ...

OBJECTIVE Cerebrospinal fluid (CSF) leaks may present as rhinorrhea or otorrhea and can lead to life-threatening complications if not detected. The usefulness of the morpholinopropanesulfonic acid (MOPS)-histidine buffer in detecting β₂-transferrin, which is only found in the cerebrospinal fluid, was compared with the standard barbital buffer. METHODS We evaluated 20 aural or nasal patient sp...

A number of methods have evolved to examine the patient with posttraumatic CSF rhinorrhea. Until the advent of metrizamide CT cisternography, radioisotope cisternography was the predominant method of investigation. Metrizamide cisternography has preempted the use of isotopes because of its more precise ability to localize the site of CSF leakage [1-5]. However, this method, which requires lumba...

A 35-year-old female complained of right-sided watery nasal discharge persisting for 2 weeks. Neuroimaging investigations revealed a defect in the lateral side of middle cranial fossa, temporal lobe encephalocele protruding into the lateral extension of the sphenoid sinus, and cerebrospinal fluid (CSF) collection on the right side of the sphenoid sinus. The transcranial approach was performed f...

In this study, we examined the role of early acetazolamide administration in reducing the risk of cerebrospinal fluid (CSF) leakage in patients with a high risk of permanent CSF leakage. In a randomised clinical trial, 57 patients with a high risk of permanent CSF leakage (rhinorrhea, otorrhea, pneumatocele or imaging-based evidence of severe skull-base fracture) were analysed. In the experimen...

Ecchordosis physaliphora (EP) is a benign notochordal remnant, which often an incidental finding; however, it can rarely present with neurological symptoms. We performed systematic review of the literature for cases symptomatic EP published in PubMed, Web Science and Embase from January 1982 to May 2023. This largest date revealed 60 including ours. Headache (55%) CSF rhinorrhea (32%) were most...

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