نتایج جستجو برای: cryptic rearrangement

تعداد نتایج: 36963  

2015
Anne-Claude Tabet Alain Verloes Marion Pilorge Elsa Delaby Richard Delorme Gudrun Nygren Françoise Devillard Marion Gérard Sandrine Passemard Delphine Héron Jean-Pierre Siffroi Aurelia Jacquette Andrée Delahaye Laurence Perrin Céline Dupont Azzedine Aboura Pierre Bitoun Mary Coleman Marion Leboyer Christopher Gillberg Brigitte Benzacken Catalina Betancur

BACKGROUND Apparently balanced chromosomal rearrangements can be associated with an abnormal phenotype, including intellectual disability and autism spectrum disorder (ASD). Genome-wide microarrays reveal cryptic genomic imbalances, related or not to the breakpoints, in 25% to 50% of patients with an abnormal phenotype carrying a microscopically balanced chromosomal rearrangement. Here we perfo...

Journal: :The American journal of surgical pathology 2009
Herbert Haack Laura A Johnson Christopher J Fry Katherine Crosby Roberto D Polakiewicz Edward B Stelow Seung-Mo Hong Brian E Schwartz Michael J Cameron Mark A Rubin Martin C Chang Jon C Aster Christopher A French

NUT midline carcinoma (NMC) is a uniformly lethal malignancy that is defined by rearrangement of the nuclear protein in testis (NUT) gene on chromosome 15q14. NMCs are morphologically indistinguishable from other poorly differentiated carcinomas, and the diagnosis is usually made currently by fluorescence in situ hybridization (FISH). As normal NUT expression is confined to testis and ovary, we...

Journal: :Journal of pediatric hematology/oncology 2010
Yung-Li Yang Shu-Rung Lin Jiann-Shiuh Chen Chih-Cheng Hsiao Kai-Hsin Lin Jiunn-Ming Sheen Chao-Neng Cheng Kang-Hsi Wu Shu-Wha Lin Sung-Liang Yu Hsuan-Yu Chen Meng-Yao Lu Hsiu-Hao Chang Ching-Tzu Yen Jing-Fang Lin Ying-Hui Su Ya-Ping Li Chien-Yu Lin Shiann-Tarng Jou Dong-Tsamn Lin

BACKGROUND The classification of B-lineage acute lymphoblastic leukemia (ALL) by specific chromosomal translocations has prognostic implications for risk-directed therapy. Reverse transcription-polymerase chain reaction (RT-PCR) assay is a useful tool for detecting fusion transcripts from common chromosomal translocations of ALL cells. METHODS Multiplex RT-PCR and nested-PCR assays were used ...

Journal: :Proceedings. Biological sciences 2016
Anahí Espíndola Megan Ruffley Megan L Smith Bryan C Carstens David C Tank Jack Sullivan

Identifying units of biological diversity is a major goal of organismal biology. An increasing literature has focused on the importance of cryptic diversity, defined as the presence of deeply diverged lineages within a single species. While most discoveries of cryptic lineages proceed on a taxon-by-taxon basis, rapid assessments of biodiversity are needed to inform conservation policy and decis...

2016
Kshitij Chandel Devi Shankar Suman Yi Wang Isik Unlu Eric Williges Gregory M Williams Randy Gaugler

BACKGROUND The Asian tiger mosquito, Aedes albopictus, is a vector of dengue, Chikungunya, and Zika viruses. This mosquito inhabits a wide range of artificial water-holding containers in urban and suburban areas making it difficult to control. We tested the hypothesis that female-driven autodissemination of an insect growth regulator could penetrate cryptic oviposition habitats difficult to tre...

1998
Wen-Hsiung Li

Cryptic genes are silenced genes that can still be reactivated by mutation. Since they can make no positive contribution to the fitness of their carriers, it is not clear why many cryptic genes in microbial populations have not degenerated into useless DNA sequences. Hall et al. (1983) have suggested that cryptic genes have persisted because of occasional strong environmental selection for reac...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده علوم انسانی و اجتماعی 1386

چکیده ندارد.

2014
Jelle Van Campenhout Sofie Derycke Tom Moens Ann Vanreusel

The discovery of morphologically very similar but genetically distinct species complicates a proper understanding of the link between biodiversity and ecosystem functioning. Cryptic species have been frequently observed to co-occur and are thus expected to be ecological equivalent. The marine nematode Halomonhystera disjuncta contains five cryptic species (GD1-5) that co-occur in the Westersche...

Journal: :Transcription 2012
José García-Martínez Guillermo Ayala Vicent Pelechano Sebastián Chávez Enrique Herrero José E Pérez-Ortín

It has been recently stated that stress-responding genes in yeast are enriched in cryptic transcripts and that this is the cause of the differences observed between mRNA amount and RNA polymerase occupancy profiles. Other studies have shown that such differences are mainly due to modulation of mRNA stabilities. Here we analyze the relationship between the presence of cryptic transcripts in gene...

1998
Barry G. Hall Shozo Yokoyama David H. Calhoun

Cryptic genes are phenotypically silent DNA sequences, not normally expressed during the life cycle of an individual. They may, however, be activated in a few individuals of a large population by mutation, recombination, insertion elements, or other genetic mechanisms. A consideration of the microbial literature concerning biochemical evolution, physiology, and taxonomy provides the basis for a...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید