BACKGROUND The purpose of this study was to compare survival and functional outcomes in patients with advanced oral cavity squamous cell carcinoma (SCC) treated with either surgery + adjuvant radiotherapy (RT) or concurrent chemoradiotherapy (CRT). METHODS Patients treated with curative intent by either surgery + RT or concurrent CRT were identified over a 6-year period (2001-2007). Disease a...

The aim of the present paper is to compare the integral dose received by non-tumor tissue (NTID) in stereotactic body radiation therapy (SBRT) with modified LINAC with that received by three-dimensional conformal radiotherapy (3D-CRT), estimating possible correlations between NTID and radiation-induced secondary malignancy risk. Eight patients with intrathoracic lesions were treated with SBRT, ...

Recent trials of IO prior to resection in locally advanced NSCLC report high rates pathological response. However, primarily irresectable patients were excluded from most studies. Moreover, there is no data on chemo-radiotherapy (CRT) after who are not amenable CRT. We hypothesized that induction may enable more receive curative treatment. enrolled 78 with borderline resectable including oligom...

Objective: To investigate patient-reported outcomes of taste alterations and quality life (QoL) in patients with nasopharyngeal carcinoma (NPC).
 Methods: In this single-center retrospective study medical records 191 NPC undergoing chemoradiotherapy (CRT) the Department Radiotherapy, Jiangsu Cancer Hospital, Affiliated Hospital Nanjing Medical University from January 2021 to December were ...

Background: The aim of this study was to compare the differences of the dosimetric parameters between three-dimensional conformal radiotherapy (3D-CRT) and simultaneous-integrated boost intensity-modulated radiotherapy (SIB-IMRT) techniques in the prone and supine positions for breast irradiation. Materials and Methods: Ten patients underwent a computed tomography simulation in both the prone a...

Background: In unresectable metastatic rectal cancers, surgery of primary tumor remains highly debated. Pelvic Chemoradiotherapy (CRT) could allow sufficient local control in order to avoid major and sometimes mutilating surgery. Dose escalated CRT increase control. The aim this study was evaluate the feasibility tolerance a with radiation dose escalation using intensity modulated radiotherapy ...

BACKGROUND The occurrence of cerebral infarction after intraarterial chemoradiotherapy (CRT) remains uncertain. METHODS We conducted a retrospective cohort study using the Diagnosis Procedure Combination (DPC) database from 2010 to 2013. We performed a 1:4 propensity score-matched analysis between patients undergoing intraarterial or intravenous CRT, and determined the association between cer...

INTRODUCTION It was reported that proton beam therapy (PBT) reduced the normal brain dose compared with X-ray therapy for pediatric brain tumors. We considered whether there was not the condition that PBT was more disadvantageous than intensity modulated photon radiotherapy (IMRT) and 3D conventional radiotherapy (3D-CRT) for treatment of pediatric brain tumors about the dose reduction for the ...

BACKGROUND Our aim was to evaluate the efficacy and toxicity of chemoradiotherapy (CRT) with transoral debulking microsurgery for T2N0 glottic cancer. METHODS Thirty patients with T2N0 glottic cancer treated with concurrent hyperfractionated radiotherapy (RT) and carboplatin were retrospectively analyzed. Median total dose of RT was 72 Gy. Nineteen of 30 patients also received transoral debul...

Neoadjuvant chemoradiation (CRT) followed by curative surgery still remains the standard of care for locally advanced rectal cancer (LARC). The main purpose of this multimodal treatment is to achieve a complete pathological tumor response (ypCR), with better survival. The surgery delay after CRT completion seems to increase tumor response and ypCR rate. Usually, time intervals range from 8 to 1...