The purpose of this investigation was to elucidate the anti-nociceptive and anti-inflammatory properties of aqueous acetone extracts from Cienfuegosia digitata Cav; and Sida Alba L. in Swiss mice, with an aim to provide a scientific basis for the traditional use of these plants in the treatment of inflammation disorders. In antiinflammatory activity, the carrageenan-induced paw edema and oil cr...

Mercury (Hg) is one of the most toxic heavy metals, and it largely used in illegal gold extraction Peru. We evaluated tolerance to Hg Paronychia microphylla Phil, Ambrosia artemisioides Willd Croton ruizianus Müll. Arg. plants, using controlled concentrations (5, 10 80 mg L-1). Two groups were identified according antioxidant enzymatic bioaccumulation response, but changes soluble protein sugg...

Charles River mice were painted once with dimethylbenz(a)anthracene (tumor initiation), followed by repeated applications of croton oil (tumor promotion). The i.v. injection of Bacillus Calmette-Guérin(BCG) 3 weeks prior to the initiation of croton oil treatment reduced the incidence and rate of appearance of both benign and malignant skin tumors. After 50 applications of croton oil, (2/week f...

The acetone extract (AcE) of the Croton bonplandianus Baill., an exotic weed of the Euphorbiaceae family was studied for cytotoxicity, apoptosis, cell cycle arrest in A549 cell line and antioxidant capacities using MTT assay, acridine orange/ethidium bromide (AO/EB staining), cell cycle analysis and DPPH radical scavenging assay respectively. Based on the cytotoxic activity, the extract was tes...

The genus Croton belongs to the family Euphorbiaceae and comprises well over 1300 species growing as trees, shrubs, and herbs in tropical and subtropical regions of both hemispheres [1]. One of its species is Croton sparsiflorus (syn. C. bonplandianus) which is a shrub growing in sandy clay soil in Asia and South America [2]. It is used as a potent hypotensive agent [3] and for the treatment of...