Crimean-Congo hemorrhagic fever virus (CCHFV) is a geographically widespread RNA virus with a high degree of genomic diversity that complicates sequence-based diagnostics. Here, we sequenced eight CCHFV strains for improved assay design and deposition into FDA-ARGOS, the FDA's pathogen database for development and verification of next generation sequencing assays.

To investigate Crimean-Congo hemorrhagic fever virus in Turkey, we conducted a seroepidemiologic survey during January-April 2009. Seroprevalence of infection was 10% in a sample from an outbreak region and increased with patient age, indicating that the virus had been previously present in Turkey. We also estimated that 88% of infections were subclinical.

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 13, No. 5, May 2007 805 8. Poirel L, Leviandier C, Nordmann P. Prevalence and genetic analysis of plasmid-mediated quinolone resistance determinants QnrA and QnrS in Enterobacteriaceae in a French University Hospital. Antimicrob Agents Chemother. 2006;50:3992–7. 9. Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. Identifi ...

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 10, No. 10, October 2004 1881 detected during the early febrile period. The male patient still had fever when the needle accident occurred, and the needle was contaminated. Infectious disease specialists and other physicians should recognize that vector-borne diseases, such as dengue and malaria, are potentially life threatening. Therefore, ...

SIK,-A case of haemorrhagic fever caused by Crimean-Congo haemorrhagic fever (CCHF) virus' in May, 1983, in a parient who lived in Selibaby, south-eastern Mauritania, prompted an epidemiological survey in this area in March, 1984. The area around Selibaby is undifferentiated dry savannah. It is an important cattle-raising area, especially during the dry season when herds migrate from the north ...

We investigated migratory birds' role in spreading Crimean-Congo hemorrhagic fever virus (CCHFV) through attached ticks. We detected CCHFV RNA in ticks on migratory birds in Turkey. Two isolates showed similarity with CCHFV genotype 4, suggesting a role for ticks in CCHFV epidemics in Turkey and spread of CCHFV by birds.

A 2009 deployment of military units from several Saudi Arabian provinces to Jazan Province, Saudi Arabia, enabled us to evaluate exposure to Alkhurma, Crimean-Congo, dengue, and Rift Valley hemorrhagic fever viruses. Seroprevalence to all viruses was low; however, Alkhurma virus seroprevalence was higher (1.3%) and less geographically restricted than previously thought.

Crimean-Congo hemorrhagic fever virus was detected in ticks removed from migratory birds in Morocco. This finding demonstrates the circulation of this virus in northwestern Africa and supports the hypothesis that the virus can be introduced into Europe by infected ticks transported from Africa by migratory birds.

conclusions this study showed that this novel one-step rrt-pcr assay is a rapid, reliable, repeatable, specific, sensitive, and simple tool for the detection of the cchf virus. results from a total of 75 suspected serum samples, 42 were confirmed to be positive for cchf virus, with no false-positives detected by the sequencing results. after 40 amplification cycles, the melting curve analysis r...