BACKGROUND Cardiopulmonary bypass and cardiac surgery are associated with a significant systemic inflammatory response that may increase postoperative complications. This meta-analysis assessed whether the benefits and risks of corticosteroid use were dose dependent in adult cardiac surgery. METHODS AND RESULTS Randomized controlled trials of the use of corticosteroid prophylaxis in adult car...

BACKGROUND The application of mycophenolate mofetil (MMF) in treating patients with immunoglobulin A nephropathy (IgAN) remains uncertain. This update meta-analysis was performed to re-evaluate the therapeutic potential of MMF in IgAN. METHODS Articles were obtained by searching the electronic databases without language restriction. Randomized controlled trials studying the role of MMF in tre...

OBJECTIVES We sought to clarify the efficacy of corticosteroid therapy for preventing atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). BACKGROUND The inflammatory process may cause acute AF recurrence after PVI. However, no studies have examined the relationship between corticosteroid administration and AF recurrence after PVI. METHODS A total of 125 patients with p...

Introduction Few data are available on the risk of SAEs in corticosteroid users in IgAN populations. We describe the prevalence and risk factors of corticosteroid-related SAEs in a Chinese cohort. Methods A total of 1034 IgAN patients were followed up in our renal center from 2003 to 2014. Prevalence of corticosteroid use and corticosteroid-related SAEs were noted. Logistic regression was use...

OBJECTIVE To identify predictors of corticosteroid prescription filling following an emergency department (ED) visit or a hospitalization for asthma. DESIGN A retrospective cohort study. PATIENTS Tennessee children (defined as those aged 2-17 years in this study) covered by Medicaid were included in the cohort if they had an ED visit or a hospitalization for asthma between July 1, 1995, and...

parking area and inside the Bella Center, with a level of 6.0¡1.7 and 3.0¡0.9 mg?m, respectively. Peak values were 12.5 mg?m and 12.0 mg?m, respectively. However, outside in front of the Bella Center with smokers, mean PM2.5 was 17.8¡7.5 mg?m with a peak of 98.9 mg?m (p,0.03, as compared with inside the venue), which is a step down in AQI. PM2.5 along the motorway was only 4.6¡0.7 mg?m with a p...

There is no consensus of treatments for acute acalculous cholecystitis with systemic lupus erythematosus (SLE). The study was aimed to investigate the effect of the corticosteroid for these patients.A series of patients who were diagnosed as acute acalculous cholecystitis with SLE in the period from January 2012 to December 2016 at our hospital were included. They accepted 2 different conservat...

Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series illustrates the occurrence of clinically significant adrenal insufficiency in asthmatic children while patients were on inhaled corticosteroid treatment and the unexp...

Symptomatic adrenal insuYciency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series illustrates the occurence of clinically significant adrenal insuYciency in asthmatic children while patients were on inhaled corticosteroid treatment and the unexpected...