endothelial dysfunction and carotid intima-media thickness are 2 indicators of subclinical cardiovascular disease. the aim of study was to analyze brachial flow mediated dilation(fmd)and carotid intima media thickness (cimt)in patients with coronary artery disease, and investigate the relationship between endothelial function, cimt and coronary artery disease risk factors.56 men and women aged ...

conclusions a significant proportion of coronary atherosclerotic plaques in cadavers with confirmed acute myocardial infarction were detected to be infected with cytomegaloviruses while no infections of c. pneumoniae and h. pylori were detected. patients and methods sixty cadavers in two equal groups were analyzed. acute myocardial infarction group included cadavers with acute myocardial infarc...

background: given the lack of consistency in the literature regarding the reliability of the ankle-brachial index (abi) as a valid screening tool and an independent risk indicator of cardiovascular events and mortality, we compared it with angiography as a reference standard test. methods: this case-control study, conducted between 2010 and 2011 in tehran heart center, recruited 362 angiographi...

materials and methods genotyping of the mia3 gene was undertaken using taqman real-time pcr in all subjects. anthropometric and biochemical features, including hdl, ldl, and tg were assessed in all subjects. results the cad patients had significantly (p < 0.05) higher bmi and significantly higher levels of tg, ldl, sbp, and dbp, while the level of hdl was lower compared to that of the control g...

more than eighty percent of patients with coronary heart diseases (chd) have conventional risk factors. prevalence of well known risk factors seems to show a different pattern in younger patients and individual above 55 years. to evaluate the pattern of conventional chd risk factors in healthy individuals in two different age groups. a large scale population based survey of 31999 individuals fr...

results during the 3 months study, in the placebo group, systolic bp (sbp) increased with 6.3 mmhg and diastolic bp (dbp) increased with 4.6 mmhg, changes which were significant. after the 3 months, the effect of garlic on sbp, after adjusting for baseline value, was significant, and this effect was more significant in hypertensive patients. plasma lipids and lipoproteins did not change signific...

background: c linical trials of revascularization have routinely under-enrolled elderly subjects. thus, symptom relief and improved survival might not apply to elderly patients, in whom the risk of mortality and disability from revascularization procedures seems to be high and co-morbidity is more prevalent. the present case control study was performed to draw a comparison in terms of the proce...

background abnormalities in the velocity and pattern of myocardial shortening on tissue doppler imaging (tdi) have been proposed to aid in the noninvasive diagnosis of coronary artery disease (cad). objectives we investigated the diagnostic value of post-systolic shortening (pss), a delayed ejection velocity of the myocardium after the closure of the aortic valve, on tdi in the diagnosis of cad...

background coronary artery disease (cad) is the most common cause of death worldwide. mef2a directly regulates target genes in the process of muscle development. this gene product is a transcription factor. mef2a protein in homodimer or heterodimer forms binds to a/t-rich cis elements with conserved sequence in promoter, regulator, and enhancer of many genes, which are determining in evolution ...