BACKGROUND Cor triatriatum is a rare congenital cardiac abnormality, consisting of an obstructing membrane between the pulmonary veins and the mitral valve in varying patterns. The entitiy can mimick the pathophysiology of mitral stenosis, necessitating surgical resection. Occasionally, percutaneous balloon dilatation of the membrane has been successfully performed. CASE PRESENTATION We repor...

AIMS One goal of total hip arthroplasty is to restore normal hip anatomy. The aim of this study was to compare displacement of the centre of rotation (COR) using a standard reaming technique with a technique in which the acetabulum was reamed immediately peripherally and referenced off the rim. PATIENTS AND METHODS In the first cohort the acetabulum was reamed to the floor followed by sequent...

A number of COR genes (COld-Regulated genes) have been implicated in the acquisition of low temperature (LT) tolerance in wheat (Triticum aestivum L.). This study compared the relative expression patterns of selected COR genes in leaf and crown tissues of wheat near-isogenic lines to increase understanding of the molecular mechanisms underlying LT acclimation. Reciprocal near-isogenic lines wer...

S. mansoni infection can produce damage in several organs, in some due to immunological altera­ tions such as the development of glomerulopathy2 and in others, at least in great part, due to vascular obstruction related to egg deposition, such as chronic cor pulmonale 1. Both situations are essentially obser­ ved in patients with the hepatosplenic form of the parasitic infection. There are repo...

A 55-year-old male was referred to the cardiologist because of the occurrence of two ischaemic strokes within five months’ time in the absence of documented atrial fibrillation. At echocardiography, a membrane was visualised in the left atrium (cor triatriatum) (Fig. 1a). Since no other abnormalities were detected, the cor triatriatum was held responsible for the cardioembolic stroke. Surgical ...

Nuclear receptors (NRs) usually bind the corepressors N-CoR and SMRT in the absence of ligand or in the presence of antagonists. Agonist binding leads to corepressor release and recruitment of coactivators. Here, we report that estrogen receptor beta (ERbeta) binds N-CoR and SMRT in the presence of agonists, but not antagonists, in vitro and in vivo. This ligand preference differs from that of ...