BACKGROUND During IVF or ICSI cycles, ovarian hyperstimulation syndrome (OHSS) is a major problem. The aim of this prospective, multicentre, comparative study (using historical controls) was to assess the efficacy of a GnRH antagonist protocol in preventing OHSS in selected patients who had experienced OHSS or had been at risk of OHSS in their previous IVF/ICSI attempt. METHODS AND RESULTS Pa...

ObjectiveTo evaluate whether physicians’ choice of ovarian stimulation protocol is associated with laboratory outcomes.DesignRetrospective cohort study.SettingSingle academic center.Patient(s)The subjects were 4,458 patients who completed more than one in vitro fertilization cycle within 1 year. On second stimulation, 49% repeated the same and 51% underwent a different one.Intervention(s)Estrad...

Isolation of cell free fetal DNA (cffDNA) from maternal serum usually leads to very low concentrations of DNA impeding further resolving through conventional methods of electrophoresis. Although several protocols have been described for capillary electrophoresis (CE) of double stranded DNA, they usually need using special polymers or coated capillaries which degrade over time. Herein, we propos...

Abstract Study question Could exogenous progestin replace the use of an antagonist GnRH (GNRH-antagonist) without any effects on embryo morphokinetics and implantation rate in freeze-all cycles? Summary answer Exogenous leads to slower development increased cyclés cancellation rate, with when compared cycles using GnRH-antagonist. What is known already Improvements cryopreservation techniques a...

objective: nano components are today’s new wonder material. however, the safety or toxicity of these components in humans is not yet clear. in a previous study we indicated that nano zno (nzno) has a stronger anxiolytic effect compared to the conventional zno (czno). the present study was designed to evaluate the intraperitoneal administration of an opioidergic receptor agonist and antagonist o...