background nonalcoholic steatohepatitis (nash) is a common liver disease that can progress to cirrhosis or hepatocellular carcinoma. it is estimated that up to 3% of the iranian population have this condition. although the pathogenesis of nash is incompletely understood, there is significant evidence pointing to the importance of insulin resistance. metformin is an oral hypoglycemic agent known...

Objectives To assess the efficacy of a new investigative treatment a non-inferiority study is undertaken when it is no longer ethical to have a placebo control. Instead an active controlled trial is undertaken. The objective is thus to show that the new treatment is no worse than the active control. In analysing a non-inferiority trial, the following ABC needs to be considered [1]: 1. The Assay...

Author Contributions: Dr Grey had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Role of the Sponsor: The Health Research Council of New Zealand had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manusc...

background: administration of albumin for burn patients and its effects on mortality and morbidity has been debated for along time. the aim of this study was to evaluate the effects of albumin administration on wound healing, length of hospital stay, weight change, and mortality of burn patients.   methods: two matched groups of patients from shiraz burn care center were randomly selected. the ...

conclusions this method is recommended for the treatment of dermal warts, owing to the effectiveness, short duration of treatment, and low cost of topical treatment for dermal warts using hd tablets. background warts are common dermatological lesion caused by skin epithelial cells’ infection with human papillomavirus (hpv). objectives this study aimed to assess the efficacy of a new method for ...

zinc deficiency during pregnancy has been related to adverse pregnancy outcomes. however, the results of zinc-supplementation trials have not been consistent in improvement of pregnancies outcomes. this study was undertaken to investigate whether zinc supplementation was associated with pregnancy complications in iranian women during the last 2 trimesters. it also assessed the anthropometric me...