The human CD2 (hCD2) locus control region (LCR) inserted in the mouse CD8 gene complex activates expression of the CD8 genes in T cell subsets in which the CD8 locus is normally silenced (e.g., CD4(+) single-positive T cells). In this article, we show that, in conditional mCD8/hCD2-LCR (CD8/LCR) knock-in mice, the continuous presence of the hCD2-LCR is required for this effect. Deletion of the ...

Visual systems that have evolved in nature appear to exercise a mechanism that places emphasis upon areas in a scene without necessarily recognising objects that lie in those areas. This paper describes the application of a new model of visual attention to the automatic assessment of the degree of DNA damage in cultured human lung fibroblasts. The visual attention estimator measures the dissimi...

We study the exact controllability of a nonlinear plate equation by the means of a control which acts on an internal region of the plate. The main result asserts that this system is locally exactly controllable if the associated linear Euler-Bernoulli system is exactly controllable. In particular, for rectangular domains we obtain that the Berger system is locally exactly controllable in arbitr...

This work presents an application of the previously proposed Support Vector Machines Based Generalized Predictive Control (SVM-Based GPC) method [1] to the problem of controlling chaotic dynamics with small parameter perturbations. The Generalized Predictive Control (GPC) method, which is included in the class of Model Predictive Control, necessitates an accurate model of the plant that plays v...

The critical period for weed control (CPWC) is the period in the crop growth cycle during which weeds must be controlled to prevent unacceptable yield losses. Field studies were conducted in 2005 and 2006 in the University of Birjand at the south east of Iran to determine CPWC of corn using a randomized complete block design with 14 treatments and three replications. The treatments consisted of...

In this paper we investigate the sub-channel assignment and power control to maximize the total sum rate in the uplink of two-cell network. It is assumed that there are some sub-channels in each cell which should be allocated among some users. Also, each user is subjected to a power constraint. The underlying problem is a non-convex mixed integer non-linear optimization problem which does not h...

Locus control regions (LCRs) are responsible for initiating and maintaining a stable tissue-specific open chromatin structure of a locus. In transgenic mice, LCRs confer high level expression on linked genes independent of position in the mouse genome. Here we show that an incomplete LCR loses this property when integrated into heterochromatic regions. Two disruption mechanisms were observed. O...

Monitoring and automatic control of building environment is a crucial application of Wireless Sensor Network (WSN) in which maximizing network lifetime is a key challenge. Previous research into the performance of a network in a building environment has been concerned with radio propagation within a single floor. We investigate the link quality distribution to obtain full coverage of signal str...

Kangal and Akbash dogs are the two well-known shepherd dog breeds in Turkey. In order to contribute to the understanding of the genetic relationship between Kangal dogs, Akbash dogs and the dogs from different regions of Eurasia, 585 base pair (bp) segment of mitochondrial DNA (mtDNA) control region was sequenced from Kangals and Akbashes. Sequences of the Kangal and Akbash dogs examined in the...

The most upstream hypersensitive site (HS) of the b-globin locus control region (LCR) in humans (58 HS 5) and chickens (58 HS 4) can act as an insulating element in some gain of function assays and may demarcate a b-globin domain. We have mapped the most upstream HSs of the mouse b-globin LCR and sequenced this region. We find that mice have a region homologous to human 58 HS 5 that is associat...