INTRODUCTION Glycerin is a rare sensitizer and is widely used for cosmetics, medicine, and food for its stable, nontoxic properties. We report on a patient with generalized urticarial eruptions who had contact urticaria syndrome caused by glycerin enema. Our case suggests that glycerin can be a cause of contact urticaria syndrome and even anaphylaxis, although allergic reactions to glycerin are...

Received: July 28, 2017 Revised: October 17, 2017 Accepted: November 02, 2017 Abstract: Background: Isocyanates are mainly considered respiratory allergens but can also cause contact allergy. Diphenylmethane-4,4′-diamine (4,4′MDA) has been considered a marker for diphenylmethane-4,4′-diisocyanate (4,4′-MDI) contact allergy. Furthermore, overrepresentation of positive patch-test reactions to p-p...

Painting mice on the skin with the diazonium salt of p-arsanilic acid elicited two types of T cell activity. One was restricted by the I region of the major histocompatibility complex and was responsible for the transfer of azobenzenearsonate (ABA) sensitivity to naive mice. The other was H-2K restricted and could be demonstrated by its ability to interact specifically with ABA-coupled cells in...

Topical anesthetic allergy is a rare but recognized entity forwhich incidence is difficult to calculate owing to the difference between a perceivedand trueallergic response.Allergic episodesattributed to topical anesthetics are typically adverse reactions, such as a vasovagal event, rather than thedevelopmentofhypersensitivity.1However, several articles place the likely incidence of topical ane...

BACKGROUND Contact allergy to local anaesthetics is relatively common. Patch testing with benzocaine in the European baseline series is recommended for diagnosis, even though a caine mix has been previously suggested to be superior. OBJECTIVES To assess the frequency and patterns of contact allergy to local anaesthetics by using a caine mix (benzocaine, tetracaine, and cinchocaine) in the bas...

Engagement of vascular endothelial (VE)-cadherin leads to the cessation of proliferation commonly known as 'contact inhibition'. We show that VE-cadherin inhibits growth by mediating changes in cell adhesion to the extracellular matrix. Increasing cell-cell contact decreased cell spreading and proliferation, which was reversed by blocking engagement of VE-cadherin. Using a new system to prevent...