Connective tissue growth factor (CCN2), a member of the CCN family of proteins, is a cysteine-rich matricellular protein. Connective tissue growth factor is not normally expressed in dermal fibroblasts unless induced. The most potent inducer of connective tissue growth factor thus far identified is transforming growth factor beta. Connective tissue growth factor, however, is constitutively over...

In vivo cultivated connective tissue is rich in lipids. That obtained from man and chicken has larger concentrations of neutral fat and cholesterol than connective tissue of other species. Connective tissue synthesizes cholesterol and possesses a striking avidity for retention of either endogenous or exogenous cholesterol. The fibrous portion of sponge-connective tissue of the rabbit incorporat...

By fractionation of human liver tissue, nuclear, mitochondrial, and connective tissue antigens were prepared. According to the results of serological tests, in conditions associated with substantial damage to the hepatic parenchyma, antibodies reacting with the nuclear and mitochondrial antigens are produced that show practically no reaction with the connective tissue antigen. It is advisable t...

Histological relationships and the distribution of junctions between myocardial cells and connective tissue were investigated in the inter-ventricular septum. Pig hearts were studied using 2 techniques: Picro-Sirius red-collagen-staining of frozen sections for connective tissue septa, and immune-staining with antibodies against Desmoplakins for intercalated discs. By overlaying serial sections ...

statement of the problem: t cells have been shown to play a role in the etiopathogenesis of periodontal disease. b7-h3, a costimulatory molecule, is found to be associated with regulation of t cell function in some tumoral tissues, as well as autoimmune and inflammatory diseases. purpose: the aim of this study was to investigate the expression of b7-h3 molecule in healthy and diseased gingival ...