Microscopic analysis of T cell-antigen-presenting cell (T cell:APC) interactions at the single cell level has been a powerful, but tedious and subjective, technique. In this paper, we describe a rapid and quantitative method to identify T cell:APC conjugates using succinimidyl ester dyes, which irreversibly label free amine groups on the cell surface. The labeled cell conjugates and subsequent ...

Conjugates of 2'-deoxyguanosine, L-tryptophan and benzophenone designed to study pathways of fast radical reactions by the photo Chemically Induced Dynamic Nuclear Polarization (photo-CIDNP) method were obtained by the phosphotriester block liquid phase synthesis. The phosphotriester approach to the oligonucleotide synthesis was shown to be a versatile and economic strategy for preparing the re...

This paper considers the problem of minimizing summation a differentiable function and nonsmooth on Riemannian manifold. In recent years, proximal gradient method its variants have been generalized to setting for solving such problems. Different approaches generalize mapping lead different versions methods. However, their convergence analyses all rely exactly, which is either too expensive or i...

Related DatabasesWeb of Science You must be logged in with an active subscription to view this.Article DataHistorySubmitted: 22 April 2020Accepted: 09 July 2021Published online: 21 October 2021Keywordslinear quadratic regulators, optimal control, nonconvex minimization, state feedback, output gradient method, convergenceAMS Subject Headings49N10, 49M37, 90C26, 90C52Publication DataISSN (print):...

in this paper imprecise target models has been proposed to investigate the relation between imprecise data envelopment analysis (idea) and mini-max reference point formulations. through these models, the decision makers' preferences are involved in interactive trade-off analysis procedures in multiple objective linear programming with imprecise data. in addition, the gradient projection type me...