BACKGROUND The risk of congenital anomalies in twins is higher than in singletons, but it is less well reported in relation to chorionicity. The aim of this study was to describe the prevalence of congenital anomalies in twin pregnancies by chorionicity and by major subtype and compare the rates with those in singletons. METHODS The study population included 2329 twin pregnancies (4658 twins)...

cleft lip and cleft palate are one of the most frequent congenital anomalies worldwide. this study was conducted in order to measure the frequency of cleft lip and palate among live births in akbar abadi hospital. this is a descriptive study, dealing with 57526 cases of live birth out of 59477 medical files in akbar abadi hospital from 2004 to 2008. all the collected data were recorded in speci...

maternal diabetes has teratogenic effects on the evolution of the fetal cardiovascular system; as a consequence, cardiovascular malformations are the most common anomalies in infants of diabetic mothers. the present study focuses on the association of all types of diabetes in mothers with the incidence of congenital cardiovascular malformations in their infants. in this retrospective case-contr...

Congenital diaphragmatic hernias (CDHs) and structural anomalies of the diaphragm are a common class of congenital birth defects that are associated with significant morbidity and mortality due to associated pulmonary hypoplasia, pulmonary hypertension and heart failure. In ∼30% of CDH patients, genomic analyses have identified a range of genetic defects, including chromosomal anomalies, copy n...

PURPOSE To assess the regional patterns of infant mortality due to lethal congenital anomalies, and the potential reasons for the regional patterns. METHOD The study analyzed 2,507 infant deaths due to lethal congenital anomalies among 1,178,452 live births in 9 of the 12 Canadian provinces and territories from 1990 to 1995 recorded in Statistics Canada's live birth and death data bases. RE...

background cutis marmorata telangiectatica congenita (cmtc) is a sporadic congenital skin vascular abnormality. significant number of patients has other congenital anomalies. case report we report a case of a preterm male newborn with cutis marmorata pattern presented on the skin of the face, right side of front of the trunk, whole back, glutei and both legs. besides, microretrognatia and asymm...

BACKGROUND Congenital and acquired airway anomalies represent a relatively common albeit challenging problem in a national tertiary care hospital. In the past, most of these patients were sent to foreign Centres because of the lack of local experience in reconstructive surgery of the paediatric airway. In 2009, a dedicated team was established at our Institute. Gaslini's Tracheal Team includes ...

STUDY OBJECTIVE To provide an international perspective on the impact of congenital anomalies on infant mortality from 1950 to 1994. DESIGN Population-based study based on data obtained from vital statistics reported to the World Health Organisation. SETTINGS 36 countries from Europe, the Middle East, the Americas, Asia, and the South Pacific. RESULTS On average, infant mortality declined...

A congenital anomaly is a physical, metabolic, or anatomic deviation from the normal pattern of development that is present at birth. Minor congenital anomalies do not have medical or cosmetic importance, but detection of more than three such anomalies may reveal the prenatal origin of a disorder. The aim of the present study was to establish an association between the presence of minor congeni...