نتایج جستجو برای: congenital infection
تعداد نتایج: 569025 فیلتر نتایج به سال:
The fetal brain is highly vulnerable to teratogens, including many infectious agents. As a consequence of prenatal infection, many children suffer severe and permanent brain injury and dysfunction. Because most animal models of congenital brain infection do not strongly mirror human disease, the models are highly limited in their abilities to shed light on the pathogenesis of these diseases. Th...
Background & Aims: Toxoplasma gondii is an important zoonotic disease. Infection with toxoplasma especially asymptomatic infection in pregnant women leads to congenital toxoplasmosis, making abortion, congenital abnormalities in the fetus, and severe damages in individuals with immunodeficiency. The aim of this study was to evaluate seroepidemiology and the risk factors of toxoplasmosis in p...
Zikavirus infection during pregnancy generates a series of neurological, musculoskeletal and sensory disorders known as Congenital Zika Virus Syndrome (CZVS), being responsible for even oral changes. This study aims to review the literature address relationship between congenital development bruxism in childhood. To achieve this goal, research was carried out by ...
Congenital Zika virus (ZIKV) infection impacts fetal development and pregnancy outcomes. We infected a pregnant rhesus macaque with a Puerto Rican ZIKV isolate in the first trimester. The pregnancy was complicated by preterm premature rupture of membranes (PPROM), intraamniotic bacterial infection and fetal demise 49 days post infection (gestational day 95). Significant pathology at the materna...
This work aims to compare the effects of acute or chronic infections with the T. cruzi genotypes TcI (X10 strain), TcII (Y strain) and TcVI (Tulahuen strain) on fertility, gestation, pup growth and the possible vertical transmission of parasites in BALB/c mice. The occurrence of congenital infection was evaluated by microscopic examination of blood and/or qPCR on blood and heart in newborn pups...
Introduction : Human cytomegalovirus (HCMV) is able to go into latency and is the most common cause of congenital infections in humans. Its clinical manifestations range from asymptomatic forms to severe fetal damage, and in rare cases, fetal death due to abortion. This prospective cross-sectional study was designed to determine the seroprevalence of HCMV infection in pregnant women attending...
In a study of congenital transmission during acute infection of Toxoplasma gondii, 23 pregnant Balb/c mice were inoculated orally with two cysts each of the P strain. Eight mice were inoculated 6-11 days after becoming pregnant (Group 1). Eight mice inoculated on the 10th-15th day of pregnancy (Group 2) were treated with 100 mg/kg/day of minocycline 48 h after inoculation. Seven mice inoculated...
complication of infection with maternal varicella before 20 weeks of pregnancy. Prospective studies in Europe and North America have shown that the incidence of congenital varicella syndrome in maternal varicella contracted in the first 20 weeks of pregnancy is about 1%–2%. Based on this estimated risk (1%), on an estimated risk of varicella infection during pregnancy of two maternal infections...
Background and Aims: Cytomegalovirus (CMV) is a member of herpesviruses. It is one of the most common cause of congenital and prenatal infections. CMV infection of pregnant women, especially in the first trimester may lead to congenital abnormalities in the newborns. The prevalence of CMV infection in developed countries is about 40% and in developing countries may be 100%. Because there is no ...
Cytomegalovirus (CMV) is the most common congenital infection and is the leading non-genetic cause of neurological defects. CMV infection in early life is also associated with intense and prolonged viral excretion, indicating limited control of viral replication. This review summarizes our current understanding of the innate and adaptive immune responses to CMV infection during fetal life and i...
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