Many nephrotoxic effects of drugs have been described, whereas the effect on renal development has received less attention. Nephrogenesis ceases at approximately 36 weeks of gestation, indicating that drugs administered to pregnant women and to preterm-born neonates may influence kidney development. Such an effect on renal development may lead to a wide spectrum of renal malformations (congenit...

Congenital uterine anomalies are often asymptomatic. They may present with infertility, recurrent miscarriage, preterm delivery, abnormal lie in pregnancy and other obstetric complications. We report the case of a 38-year old patient with unicornuate uterus without rudimentary horn and with unilateral left ovarian agenesis and unilateral left renal agenesis who gave birth to eleven children. An...

Congenital agenesis of lumbar vertebrae was diagnosed in a day-old female lamb based on radiology and clinical examinations. There was no neurological deficit in hindlimb and forelimb associated with standing disability. Radiography of the abdominal region revealed absence of lumbar vertebrae. Necropsy confirmed clinical and radiographic results. No other anomaly or agenesis was seen macroscopi...

in cases of congenital esophageal stenosis due to tracheobronchial remnants, symptoms of partial esophageal obstruction appear at the time of weaning or during early childhood. in the absence of esophagitis, esophagram combined with cinefluoroscopy demonstrates fixed stenosis of distal esophagus and appears to be diagnostic. dilatation of rigid stenosis is invariably unrewarding and surgical re...

Six inbred persons (five males and one female) in three generations of a single family are reported as having simple congenital absence of skin on the upper or lower limbs or both. The data suggest an autosomal recessive pattern of inheritance for this apparently new clinical entity.

ABSTRACT: This report described the clinical and pathological aspects of open spina bifida diplomyelia along with multiple congenital malformations in a Texel lamb. Clinically, paresis thoracic limbs, paralysis pelvic limbs cutaneous opening lumbosacral region were observed. At necropsy, there was focally extensive disruption skin associated an absence dorsal portions vertebrae. Additionally, l...