We have evaluated Roche Diagnostics' RIA-CEA and Abbott Diagnostics' EIA-CEA methods for precision, normal reference interval, concordance, and correlation of malignant disease with increase in carcinoembryonic antigen (CEA) in plasma. In examining concordance, we used data on 138 patients with primary carcinomas of the breast, colon, lung, or pancreas, each further classified by extent of diss...

Cytological samples are often the only diagnostic material available for confirmation of lung cancer (LC) diagnosis. The aim present study was to evaluate cytology-histology concordance diagnosis, histological subtyping and molecular profiling LC, determine factors which may affect sample adequacy or concordance. 118 patients with histologically cytologically confirmed LC were retrospectively s...

PURPOSE We hypothesized that regional cerebral oxygen saturation (rSO2) could replace jugular bulb oxygen saturation (SjvO2) in the steep Trendelenburg position under pneumoperitoneum. Therefore, we evaluated the relationship between SjvO2 and rSO2 during laparoscopic surgery. MATERIALS AND METHODS After induction of anesthesia, mechanical ventilation was controlled to increase PaCO2 from 35 ...

BACKGROUND As the popularity of transcriptomic analysis has grown, the reported lack of concordance between different studies of the same condition has become a growing concern, raising questions as to the representativeness of different study types, such as non-human disease models or studies of surrogate tissues, to gene expression in the human condition. METHODS In a comparison of 33 micro...

Abstract The choice of a loss function is critical part in machine learning. This paper evaluates two different functions commonly used regression-task dimensional speech emotion recognition — error-based and correlation-based functions. We found that using with concordance correlation coefficient (CCC) resulted better performance than mean squared error (MSE) absolute (MAE). evaluations were m...