objective: although treatments with demonstrated efficacy exist for obsessive-compulsive disorder (ocd) researches on the effectiveness of combined treatment versus psychotherapy or drug treatment are controversial. the aim of this study was to compare the efficacy of metacognitive therapy (mct), fluvoxamine and the combination of mct with fluvoxamine treatment in treating patients with ocd. me...

background: obsessive-compulsive disorder (ocd) symptoms and the related disorders are subsumed under chronic psychiatric disorders which are of psychosocial and therapeutic importance. in most studies, the mean age of onset of significant ocd symptoms is adolescence period. the aim of this study was to evaluate ocd symptoms, tic disorder, body dysmorphic disorder (bdd) and trichotilomania amon...

OBJECTIVE A substantial body of evidence suggests that obsessive-compulsive disorder has a genetic component, and substantial candidate genes for the disorder have been investigated through association analyses. A particular emphasis has been placed on genes related to the serotonergic system, which is likely to play an important role in the pathogenesis of obsessive-compulsive disorder. The ge...

abstract background and aim: the intolerance of uncertainty model was initially developed as an explanation for worry within the context of generalized anxiety disorder. however, recent research has identified intolerance of uncertainty (iu) as a transdiagnostic maintaining factor across the anxiety disorders. the aim of the present study was to compare the intolerance of uncertainty in patient...

OBJECTIVE Problems with inhibiting certain pathological behaviors are integral to obsessive-compulsive disorder (OCD), trichotillomania, and other putative obsessive-compulsive spectrum disorders. The authors assessed and compared motor inhibition and cognitive flexibility in OCD and trichotillomania for the first time, to their knowledge. METHOD The Stop-Signal Task and the Intradimensiona/E...

Introduction Obsessive-compulsive disorder (OCD) is a clinical syndrome whose hallmarks are excessive, anxiety-evoking thoughts and compulsive behaviours that generally recognized as unreasonable, but which cause significant distress impairment. OCD may also occur in the context of other neuropsychiatric disorders, most commonly anxiety mood disorders. The question remains to whether these comb...