the purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. a 32 full factorial design was employed to study the effect of independent variables like carbopol-934p and hydroxypropyl methylcellulose k100m, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...

In this paper, the Accumulative Channel-die Compression Bounding (ACCB) method is investigated as a new method of severe plastic deformation to produce Nano-crystalline bulk metals on the basis of pressing in a channel mold. Aluminum as One of the most usable metal in industry is processed using this method. Analyzing the processed samples show that after four passes of ACCB method, the ultimat...

Mechanics of CNT-reinforced nano-cellular PMMA nanocomposites are investigated using coarse-grained molecular dynamics simulations. Firstly, static uniaxial stretching of bulk PMMA polymer is simulated and the results are compared with literature. Then, nano-cellular foams with different relative densities are constructed and subjected to static uniaxial stretching and obtained stress-strain cu...

The reliability analysis method and the allowable stress method were both applied in this study to determine design values of ultimate compression strength (UCS) of visually-graded 40 x 65 mm dimension Chinese larch lumber. A total of 784 lumber samples were tested on the static full-size compression strength, according to Chinese National Standards. The goodness-of-fit for the UCS distribution...

The paper presents evaluation of correlations for calculation of concrete compression strength using nondestructive testing parameters for both impact and ultrasonic pulse methods, as listed in EN 13791:2007. This standard indicates procedures relating to compression strength determination in construction and building elements. These procedures relate to compression strength evaluation based ei...

The recovery behavior for strength and impermeability of cementitious composites embedded with organic microcapsules was investigated in this study. Mortar specimens were formed by mixing the organic microcapsules and a catalyst with cement and sand. The mechanical behaviors of flexural and compression strength were tested. The results showed that strength could increase by up to nine percent w...

Fiber reinforced concretes (FRCs) exhibit property improvement caused by the fibers. By using gamma radiation we have further improved mechanical properties of hydraulic concretes elaborated with Portland cement, water, silica sand, marble and polypropylene (PP) fibers. Compression strength, compression modulus, impact strength and dynamic elastic modulus were determined. Impact fatigue testing...

Aim: The objective of this work was to study the effects of formulation variables on the release kinetics of paracetamol tablet formulation. Materials and Methods: Paracetamol tablets were formulated using wet granulation (WG) and direct compression (DC) using two predetermined pressures. Avicel, dicalcium phosphate (DCP) and pregelatinized starch (PGS) were used as directly compressible...

STATEMENT OF PROBLEM Denture tooth fracture or debonding remains a common problem in removable prosthodontics. PURPOSE The purpose of this in vitro study was to explore factors determining failure strengths for combinations of different denture tooth designs (shape, materials) and injection or compression molded denture base resins. MATERIAL AND METHODS Three central incisor denture tooth d...

The present study aims at developing A356/Al2O3(np) nano-composite with a novel and cost effective method for attaining homogeneous dispersion of Al2O3 nanoparticles in the Al matrix. In the current research, Al micro powders distributed on aluminum foil and then Al2O3 nanoparticles ultra-sounded in ethanol and sprayed on Al substrate. Subsequently, the sandwich foil was added to molten A356 du...