OBJECTIVE Applications for Abdominal Wall Vascularized Composite Allotransplantation may expand if a functional graft with decreased immunosuppressive requirements can be designed. We hypothesize that it is anatomically feasible to prepare a functional, innervated, and vascularized abdominal composite graft using a multilayered component separation technique. Including vascularized bone in the ...

Introduction. Although several intercalary reconstructions after resection of a lower extremity malignant bone tumor are reported, there are no optimal methods which can provide a long-term reconstruction with fewest complications. We present the outcome of reconstruction using a devitalized autograft and a vascularized fibula graft composite. Materials and Methods. We conducted a retrospective...

We have synthesized calcium phosphate-based, strontium (Sr) containing, porous ceramic granules for use as bone graft substitutes. The granules with a particle size between 1 and 2 mm and a (macro)-pore size around 200–500μm were mixed with a fibrin sealant to form a moldable composite material. The starting material with Sr contents between 0 and 100% Sr were precipitated from Ca/Sr solutions ...

OBJECTIVE Biological aortic valve conduits are rarely used because of the concern that possible structural valve deterioration would require complete conduit replacement in a technically demanding operation. The aim of the study was to evaluate the 10-year experience with complete aortic-root replacement using a modified composite graft in which biological valve prosthesis was located inside th...

Highlights The article outlines the modern concept of arterial myocardial revascularization, presents most promising directions for development coronary surgery, and describes results prospects clinical application autogenous grafts using two internal thoracic arteries in various graft configuration situ, making it possible to assess effectiveness procedure. Abstract There are many approaches a...

Improved survival of patients with extensive burn injuries requires the development of better techniques for timely and permanent closure of the full-thickness wound. We developed procedures for establishing confluent, stratified layers of cultured, autologous keratinocytes on the surface of a modified collagen-glycosaminoglycan membrane that contains autologous fibroblasts. We transferred the ...

Peripheral Arterial Disease (PAD) in diabetic patients is a significant cause of Morbility. Long arterial occlusion patient previously treated can require unusual and complex solution. Herein we report case complicated bypass with history for bilateral popliteal aneurysm. A 51-year-old male, smoker, hypertension diabetes mellitus was referred to our hospital rest pain left limb peripheral cyano...

In patients after extensive burn injury the lack of split thickness skin graft donor sites, and consecutive delay in wound closure are critical factors of morbidity and mortality. In addition limited functional and aesthetic results after transplantation of split thickness skin grafts present a socioeconomic problem. For improved wound closure the aim of this study was the development of a one ...

BACKGROUND Coronary revascularization trials often use a composite endpoint of major adverse cardiac and cerebrovascular events (MACCE). The usual practice in analyzing data with a composite endpoint is to assign equal weights to each of the individual MACCE elements. Noninferiority margins are used to offset effects of presumably less important components, but their magnitudes are subject to b...