In neurological disorders such as Parkinson's disease, examination of the living brain by high-resolution positron emission tomography (PET), combined with the appropriate pharmacokinetic and physiological analyses, can provide valuable quantitative information of altered brain function. The primary objective of the thesis is accomplished by developing a volumetric process for the quantitative ...

The aim of the study was to investigate intramuscular pharmacokinetics enrofloxacin in black vultures (Coragyps atratus). a single dose (10 mg/kg) studied six vultures. Plasma concentrations and its active metabolite, ciprofloxacin, were determined by high-performance liquid chromatography (HPLCuv). Pharmacokinetic parameters estimated using non-compartmental compartmental analysis. After admin...

Standard procedures for the tracing of ion fluxes into roots of plants are described here, with emphasis on cations, especially potassium (K(+)). We focus in particular on the measurement of unidirectional influx by use of radiotracers and provide a brief introduction to compartmental analysis by tracer efflux (CATE).

Compartmental network modelling is compared with the bond graph approach. Whilst both approaches build on the conservation principle, the compartmental network approach is on a slightly higher level and more compact. Also no analogies must be used, the concepts of physics are used directly in connection whilst system theoretical arguments define consistency and solvability, being roughly equiva...

Students can be provided insight into processes of enzyme kinetics and physiology via compartmental models. Graphical modelling software supports this. In this paper we discuss various models that students could implement and use to investigate blood alcohol concentration after consumption of one or more alcoholic drinks. Results from these computer models are compared with measured data that w...