نتایج جستجو برای: comparative proteomics

تعداد نتایج: 274279  

2016
Aleix Sala-Vila Inmaculada Navarro-Lérida Miguel Sánchez-Alvarez Marta Bosch Carlos Calvo Juan Antonio López Enrique Calvo Charles Ferguson Marta Giacomello Annalisa Serafini Luca Scorrano José Antonio Enriquez Jesús Balsinde Robert G. Parton Jesús Vázquez Albert Pol Miguel A. Del Pozo

The mitochondria-associated membrane (MAM) is a specialized subdomain of the endoplasmic reticulum (ER) which acts as an intracellular signaling hub. MAM dysfunction has been related to liver disease. We report a high-throughput mass spectrometry-based proteomics characterization of MAMs from mouse liver, which portrays them as an extremely complex compartment involved in different metabolic pr...

Journal: :Data in brief 2016
Tue Bjerg Bennike Kenneth Kastaniegaard Simona Padurariu Michael Gaihede Svend Birkelund Vibeke Andersen Allan Stensballe

Large repositories of well characterized RNAlater preserved samples and formalin-fixed, paraffin-embedded samples have been generated worldwide. However, the impact on the proteome of the preservation methods remain poorly described. Therefore, we analyzed the impact on the proteome of preserving samples in RNAlater, and by formalin-fixation, paraffin-embedding on human soft tissue, using direc...

Journal: :Journal of biochemistry and molecular biology 2004
Jin-Won Jung Weontae Lee

The discovery of biochemical and cellular functions of unannotated gene products begins with a database search of proteins with structure/sequence homologues based on known genes. Very recently, a number of frontier groups in structural biology proposed a new paradigm to predict biological functions of an unknown protein on the basis of its three-dimensional structure on a genomic scale. Struct...

2016
Philip Carella Daniel C. Wilson Christine J. Kempthorne Robin K. Cameron

The plant vascular system, composed of the xylem and phloem, is important for the transport of water, mineral nutrients, and photosynthate throughout the plant body. The vasculature is also the primary means by which developmental and stress signals move from one organ to another. Due to practical and technological limitations, proteomics analysis of xylem and phloem sap has been understudied i...

Journal: :Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 2012
H Hajjaran B Azarian M Mohebali R Hadighi A Assareh B Vaziri

In order to define the protein expressional changes related to the process of meglumine antimoniate resistance in anthroponotic cutaneous leishmaniasis (CL), we performed a comparative proteomics analysis on sensitive and resistant strains of Leishmania tropica isolated from Iranian CL patients. Cell proteins were analysed with 2-dimensional electrophoresis and differentially expressed proteins...

2017
Anna Shevchenko Yimin Yang Andrea Knaust Jean-Marc Verbavatz Huijuan Mai Bo Wang Changsui Wang Andrej Shevchenko

Lamp illuminants evidence the exploitation of natural resources, animal and plant domestication, commerce, religious practices and nutrition of ancient populations. However, the physicochemical analysis of their major constituent-burned, degraded and aged mixture of triacylglycerols is imprecise and may lead to ambiguous interpretations. We applied proteomics to analyze fuel deposits from eight...

2015
Wen Sang Zeng-Rong Huang Yi-Ping Qi Lin-Tong Yang Peng Guo Li-Song Chen

Here, we provide the data from a comparative proteomics approach used to investigate the response of boron (B)-tolerant 'Xuegan' (Citrus sinensis) and B-intolerant 'Sour pummelo' (Citrus grandis) leaves to B-toxicity. Using two-dimensional gel electrophoresis (2-DE) technique, we identified 50 and 45 protein species with a fold change of more than 1.5 and a P-value of less than 0.05 from B-toxi...

Journal: :Journal of proteomics 2014
Hao-Long Zeng Xiaoping Rao Lei-Ke Zhang Xiaolu Zhao Wei-Ping Zhang Jie Wang Fuqiang Xu Lin Guo

UNLABELLED Olfactory sensory information is processed and integrated by circuits within the olfactory bulb (OB) before being sent to the olfactory cortex. In the mammalian OB, neural activity driven by external stimuli can lead to experience-dependent changes in structures and functions. In this study, quantitative proteomics techniques were employed to study proteome-wide changes in the OB und...

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