background traditional medicines are among the oldest medicines and their extensive use in the recent years reflects the public’s interest in alternatives to conventional medicine. objectives the aim of this study was to investigate the genotoxicity of dillsun herbal medicine in dna damage of rat hepatocytes compared to sodium dichromate using a comet assay technique. materials and methods male...

Cumulative exposure to oestrogen has been linked to increased risk of breast cancer. Whilst oestrogens induce cancers in rodent bioassays it is unclear whether the mechanisms involved are genotoxic and/or epigenetic. The cytokinesis block micronucleus (CBMN) and the alkaline single cell-gel electrophoresis 'Comet' assays were used to examine MCF-7 cells for chromosomal damage and DNA single-str...

Some simplemolecules in comet comae like CO, C2, C3, CN, H2CO appear to be distributed in such a way that they are neither directly emitted from the nucleus surface nor created as daughter molecules from more complex gas phase species. The only remaining possible source is the organic component in comet dust. The requirements imposed on the comet dust grains by the distributed CO emission are t...

PURPOSE To compare the clinical results of cultivated oral mucosal epithelial cell sheet transplantation (COMET) of substrate-free sheets with those of COMET of amniotic membrane (AM)-based sheets. METHODS Sixteen eyes receiving COMET of substrate-free sheets (substrate-free group) were studied retrospectively and compared with disease-, age-, and ocular surface status-matched eyes undergoing...

DNA fragmentation is considered an important parameter of semen quality, and of significant value as a predictor of male fertility. Poor quality chromatin is closely associated with, and highly indicative of, some fertility problems. Many methodologies to assess DNA fragmentation in spermatozoa are available, but they are all unable to differentiate between single-stranded DNA breaks (SSB) and ...

We have calculated the thermal emission spectrum of the dust of comet P/Borrelly (1994l), a short-period comet (Jupiter family), from 3 μm to 14 μm as well as the 10 μm silicate feature in terms of the comet dust model as porous aggregates of interstellar grains. Compared to comet P/Halley dust, the dust grains of P/Borrelly appear to be relatively more processed (more carbonized), less fluffy,...

Plasticity of User Interfaces (UIs) refers to the ability of UIs to withstand variations of context of use () while preserving usability. This paper presents COMET, a software architecture style for building task-based plastic interactors. COMET bridges the gap between two main approaches in plasticity: model-driven engineering and interactors toolkits. Interactors ...

We obtained high-resolution (λ/ λ∼ 25,000) spectra of Comet C/1999 H1 (Lee) on UT 1999 August 19.6 and 21.6 using the cross-dispersed Near InfraRed SPECtrometer (NIRSPEC) at the Keck Observatory atop Mauna Kea, HI. Here we present spectra of Comet Lee between 2.874 and 3.701 μm (3479–2702 cm−1) representing the most complete high-resolution infrared survey of a comet to date in this wavelength ...

The Near-Earth Object Wide-field Infrared Survey Explorer (NEOWISE) mission observed comet C/2013 A1 (Siding Spring) three times at 3.4 μm and 4.6 μm as the comet approached Mars in 2014. The comet is an extremely interesting target since its close approach to Mars in late 2014 will be observed by various spacecraft in-situ. The observations were taken in 2014 Jan., Jul. and Sep. when the comet...

Coexposure to heavy metals occurs in many occupational settings, such as automobile refining shops, pigment, and batteries production. Heavy metals around automobile refining shops were tested for their ability to induce synergistic cytogenetic effects in Trifolium repens L. by using the chromosomal aberrasions (CAs), micronucleus (MN) and comet assay. A significant increase in micronucleus (MN...