Background and aims: Among all cancers, colon cancer is common and deadly, yet preventable. The estimated worldwide incidence of colon cancer is more than one million new cases per year. This study was done to identify the epidemiological features and risk factors of colon cancer in different regions of Birjand. Methods: This retrospective, descriptive an...

4 Chapter Is INTRODUCTION 5 Chapter 2: INCIDENCE AND DISTRIBUTION OF 10 HUMAN COLORECTAL CARCINOMA Chapter 3: EXPERIMENTAL COLORECTAL CARCNOGENESIS 19 Chapter 4: THE AETIOLOGY OE COLORECTAL CANCER 33 A Heredity 34 B Adenoma 39 C Diet 43 D Inflammation 36 E Injury 60 Chapter 3: INTESTINAL CELL PROLIFERATION 65 Chapter 6: SMALL BOWEL ADAPTATION 72 Chapter 7: ADAPTATION AND CARCINOGENESIS 86 IN TH...

Background: The equine colic, which is caused by the presence of enteroliths that are most often found in the small or large colon, is typical for certain geographical regions (dry and hot climate). A diet rich in alfalfa is one of the highest risk factors. The earliest symptoms include weight loss and repeated episodes of colic pain. Aims: To present the resul...

Background and aim: Colon cancer is the third most prevalent cancer in Iran. Prolonged colon inflammation is an important factor, in the development of colon cancer. Ginger has anti-inflammatory properties due to its content of [6]-gingerol and hence can play a role in the prevention of colon cancer. In this research the effects of ginger extract on reducing expression of the C...

conclusions administration of albumin compared to hes in patients with a normal renal function results in a lower drop of gfr and platelet count, less bleeding and lower rise of serum creatinine. background the ideal strategy to prime the cardiopulmonary bypass (cpb) circuit in adult cardiac surgery is still a matter of debate. objectives in this retrospective study, we examined albumin solutio...

Objective(s): Apatinib recently has been used to treat patients with gastric cancer, but the function of apatinib in colon cancer remains unclear. This study was conducted to investigate the impacts of apatinib on the biological function and its potential mechanism of colon cancer cells in vitro. Materials and Methods:The effect of apatinib in colon cancer cells were detected by assessing cell ...

Background: Major leg wound complications after coronary artery bypass graft procedures are infrequent and few are reported in the litrature.We present our experience in treating 30 patients with major leg wound complications after coronary revascularization procedures. Materials and Methods: A retrospective review of 2100 bypass procedures with saphenous veingraft performed over a 5-years p...

Am J Surg 1999; 178:570 –2 83. Yap CH, Lau L, Krishnaswamy M, Gaskell M, Yii M: Age of transfused red cells and early outcomes after cardiac surgery. Ann Thorac Surg 2008; 86:554 –9 84. van de Watering L, Lorinser J, Versteegh M, Westendord R, Brand A: Effects of storage time of red blood cell transfusions on the prognosis of coronary artery bypass graft patients. Transfusion 2006; 46:1712– 8 8...

When epithelia become too crowded, some cells are extruded that later die. To extrude, a cell produces the lipid, Sphingosine 1-Phosphate (S1P), which activates S1P₂ receptors in neighboring cells that seamlessly squeeze the cell out of the epithelium. Here, we find that extrusion defects can contribute to carcinogenesis and tumor progression. Tumors or epithelia lacking S1P₂ cannot extrude cel...

Aortoenteric fistula is a rare but potentially fatal condition causing massive gastrointestinal bleeding. In particular, double primary aortoenteric fistulae are vanishingly rare. We encountered a 75-year-old male patient suffering from abdominal pain, hematochezia, hematemesis, and hypotension. His computed tomography images showed abdominal aortic aneurysm and suspected aortoenteric fistulae....