We present a comprehensive micro- and macrorheological study of the effect of weak depletion attraction (Ψdep ≈ 1-10 kBT) on dense colloidal suspensions stabilized by short-range repulsive interactions. We used aqueous polymer dispersions as model system and demonstrated the unique capabilities of multiple particle tracking (MPT) to disclose structural changes in such technically important syst...

A combination of confocal microscopy and rheology experiments, Brownian dynamics (BD) and molecular dynamics (MD) simulations and mode coupling theory (MCT) have been applied in order to investigate the effect of shear rate on the transient dynamics and stress-strain relations in supercooled and glassy systems under shear. Immediately after shear is switched on, the microscopic dynamics display...

Liquid crystal suspensions including variousmicroand nano-colloidal particles have recently been received great attention for many practical applications such as nanosensors and devices, etc. When large colloidal particles of micronscale are dispersed in a uniform nematic liquid crystal phase, the colloidal particles disturb a long-range orientational order of the nematic phase. For a strong an...

An improved strategy for finding the ab initio global minimum of SixHy clusters based on a cluster genetic algorithm (CGA) is presented. Four new mutation operators are introduced which better facilitate retention of desirable structural features between the different generations of clusters in the CGA. The new CGA generally finds global minima with fewer energy evaluations and is now able to f...

Quality control systems monitor and stop translation at some ribosomal stalls, but it is unknown if halting translation at such stalls actually prevents synthesis of abnormal polypeptides. In yeast, ribosome stalling occurs at Arg CGA codon repeats, with even two consecutive CGA codons able to reduce translation by up to 50%. The conserved eukaryotic Asc1 protein limits translation through inte...

The need for nodes to be able to generate their own address and verify those from others, without relying on a global trusted authority, is a well-known problem in networking. One popular technique for solving this problem is to use self-certifying addresses that are widely used and standardized; a prime example is cryptographically generated addresses (CGA). We re-investigate the attack models...

BACKGROUND Current diagnosis and staging of neuroendocrine tumors (NETs) are significantly improved by the introduction of the chromogranin A (CgA) assay in plasma or serum as a tumor marker, and by the use of somatostatin receptor scintigraphy (SRS) for tumor localization. However, the clinical role of CgA assay compared with SRS in the management of NETs has not been well elucidated. PATIEN...

CONTEXT The majority of patients with head and neck paragangliomas (HNPGL) have biochemically silent tumours. Chromogranin A (CgA) is a tumour marker for neuroendocrine tumours. OBJECTIVE To assess the role of CgA as a tumour marker in patients with hereditary HNPGL. PATIENTS AND METHODS We included 95 consecutive patients with hereditary HNPGL for screening of plasma CgA levels and catecho...

Oxidative stress has an important role in the degradation, oxidation, cross‑linking and aggregation of lens proteins, and can trigger lens epithelial cell apoptosis. To investigate the protective effect of chlorogenic acid (CGA) against hydrogen peroxide (H2O2)‑induced oxidative stress, human lens epithelial cells (hLECs) were exposed to various concentrations of H2O2 in the presence and absenc...

OBJECTIVES Chromogranin A (CgA) and neuron-specific enolase (NSE) are biomarkers for neuroendocrine tumors. Although the knowledge of their biological variation (BV) is critical, only one study for CgA and no data for NSE are available. We report a definitive assessment of BV components of these biomarkers in the same cohort of subjects by an accurately experimental protocol. DESIGN AND METHO...