نتایج جستجو برای: coefficient cα
تعداد نتایج: 170285 فیلتر نتایج به سال:
We introduce a model of bargaining among groups, and characterize a family of solutions using a Consistency axiom and a few other invariance and monotonicity properties. For each solution in the family, there exists some constant α ≥ 0 such that the "bargaining power" of a group is proportional to cα, where c is the cardinality of the group. Subject classification: JEL C71, C78
This work presents a novel C-C distance dependent force field which is successful in selecting native structures from an ensemble of high resolution near-native conformers. An enhanced and diverse protein set, along with an improved decoy generation technique, contributes to the effectiveness of this potential. High quality decoys (structures with low root mean square deviation with respect to ...
Binding isotope effects for l-aspartate reacting with the inactive K258A mutant of PLP-dependent aspartate aminotransferase to give a stable external aldimine intermediate are reported. They provide direct evidence for electronic ground-state destabilization via hyperconjugation. The smaller equilibrium isotope effect with deazaPLP-reconstituted K258A indicates that the pyridine nitrogen plays ...
The main aim of the present paper is to establish some norm and numerical radius inequalities for the composite operator BA under suitable assumptions for the transform Cα,β (T ) := (T ∗ −αI) (β I−T ) , where α ,β ∈ C and T ∈ B(H), of the operators involved. Mathematics subject classification (2000): Primary 47A12, 47A30; Secondary 47A63..
MOTIVATION Backbone structures and solvent accessible surface area of proteins are benefited from continuous real value prediction because it removes the arbitrariness of defining boundary between different secondary-structure and solvent-accessibility states. However, lacking the confidence score for predicted values has limited their applications. Here we investigated whether or not we can ma...
Meprin metalloproteases are abundantly expressed in the brush-border membranes of kidney proximal tubules. Meprins are implicated in ischemia-reperfusion (IR)-induced renal injury and diabetic nephropathy. The protein kinase A (PKA) signaling pathway modulates extracellular matrix metabolism in diabetic kidneys. The present study evaluated isoform-specific interactions between the catalytic sub...
PURPOSE The clinical success of the first-in-class proteasome inhibitor bortezomib (VELCADE) has validated the proteasome as a therapeutic target for treating human cancers. MLN9708 is an investigational proteasome inhibitor that, compared with bortezomib, has improved pharmacokinetics, pharmacodynamics, and antitumor activity in preclinical studies. Here, we focused on evaluating the in vivo a...
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