Polymers of intrinsic microporosity (PIMs), such as the archetypal spirobisindane-based PIM-1, are among most promising new materials for making gas separation membranes with high permeance potential use in high-throughput applications. Here it is shown that ultrapermeable PIMs can be prepared by fusing rigid and bulky triptycene (Trip) to spirobisindane (SBI) unit. PIM-SBI-Trip its copolymer P...

many properties of chemicals depend on their stereochemistry. among these, the effects of stereoisomerism on percutaneous absorption of drugs are not well studied. we have previously shown that permeation of tretinoin and isotretinoin (two geometric isomers) through hydrophilic enhancers-treated rat skin is stereoselective. as, depending on their lipophilicity, penetration enhancers can change ...

Lipoxygenase(LOX) catalyzes irreversible transfer of oxygen molecule to Arachidonic and Linoleic acid to produce 13 Hydroproxy Octadecadienoic acid. Recent studies showed the involvement of Lipoxygenase products, leukotrienes, in inflammations and Lipoxygenase pathways acts as mediators of early inflammatory events in atherosclerosis. The aim of the present study was purification and characteri...

Cellulose acetate (CA) is an attractive membrane polymer for CO2 capture market. However, its low permeability hampers application as part of a most relevant types containing feeds. This work investigates the enhancement CA separation performance by incorporating ionic liquid-like pendants (1-methylimidazol, 1-methylpyrrolidine, and 2-hydroxyethyldimethylamine (HEDMA) on backbone. These CA-base...

in this work we sought to determine whether vesicles (liposomes/niosomes) were able to enhance finasteride concentration in the dermis layer, including the pilosebaceous units (psu). such enhancement could be beneficial in the treatment of some androgen-related skin disorders. hamster flank skin was used to study  3hfinasteride permeation via vesicles and a hydroalcoholic solution (ha). the dru...

Although permeation of hydrocarbons such as Benzene, Toluene, Ethybenzene, and Xylene (BTEX) through polyethylene (PE) pipe in potable water applications is rarely occurred. It is important to understand permeation mechanism and characterize the potential health risk. The most common potential hydrocarbon substances are originated from gasoline leaks. Previous research has shown that pipe mater...

Bilayer asymmetry in the apical membrane may be important to the barrier function exhibited by epithelia in the stomach, kidney, and bladder. Previously, we showed that reduced fluidity of a single bilayer leaflet reduced water permeability of the bilayer, and in this study we examine the effect of bilayer asymmetry on permeation of nonelectrolytes, gases, and protons. Bilayer asymmetry was ind...

the main goal of this work was to synthesize and evaluate the effect of dehydration temperature on the potential application of hydroxy sodalite zeolite membrane. hydroxy sodalite zeolite membranes were synthesized via direct hydrothermal method onto a tubular alumina support without seeding in a hot air oven. the synthesized membranes were characterized by x-ray diffraction (xrd) and scanning ...