Since the 1950s, rubber tree (Hevea brasiliensis) has significantly contributed to Malaysia's agricultural economy due its capability produce high-value natural rubber. Due presence of cis-1,4-polyisoprene, exhibits unique properties such as flexibility, high elasticity, and efficient heat dispersion. Cis-1,4-polyisoprene is synthesized via two distinct metabolic pathways: isoprenoid biosynthes...